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Impairment clinical trials

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NCT ID: NCT05216536 Completed - COVID-19 Clinical Trials

Physical and Cognitive Impairments in People Suffering From Long COVID

Start date: January 2, 2022
Phase:
Study type: Observational

Of the 1,900,000 Canadians who have been infected by COVID-19, 8 to 15% will continue to experience COVID-19 related symptoms well after 12 weeks. The persistence of such symptoms is now defined as "long COVID" syndrome. Current evidence does not provide a clear understanding of the physical and cognitive impairments and functional limitations that persons with long COVID present. The objectives of this project are to describe the physical and cognitive impairments and functional limitations experienced by people with long COVID and compare the evolution over 6 months of people from three separate groups: a group of people with long COVID (long COVID Group), another group of people who contracted COVID-19 but did not experience persistent symptoms (acute COVID Group), and a group of people who did not contract COVID-19 (Control Group). One hundred and twenty adults in each of the three groups will be recruited and will take part in three evaluations within 6 months (baseline and 3 and 6 months after baseline). At baseline, all participants will complete questionnaires on sociodemographics, COVID symptomatology and comorbidity, and self-reported questionnaires on quality of life, functional status, sleep, pain-related disabilities, anxiety, depression, fatigue and cognitive function. Then, physical and cognitive tests will be performed in a laboratory to provide complementary results on impairments and functional limitations. Finally, participants will wear a fitness tracker watch to monitor their activity and sleep for 7 days. The participants will complete the same measures (questionnaires, lab measures, fitness tracker watch) at 3 and 6 months after baseline evaluations. This project will lead to a better understanding of the impairments/limitations experienced following COVID-19. Hence, these results will allow to identify the interventions needed by the population and ensure these are offered through effective healthcare pathways.

NCT ID: NCT05122429 Completed - Anxiety Clinical Trials

Asynchronous Techniques for the Delivery of Empirically Supported Psychotherapies

Start date: November 6, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to test the feasibility, acceptability and efficacy of methods for delivering mental health support when real-time communication is not possible (e.g. on long duration space flights where communication lags of up to 45 minutes are anticipated). The investigators hypothesize that the two enhanced treatment conditions (i.e., those with therapist support) will outperform the online self-management program without support. The investigators also predict that outcomes for the two enhanced conditions will be comparable to those reported in the literature for in-person psychotherapy programs.

NCT ID: NCT04869891 Completed - Physical Activity Clinical Trials

How Much The Self-Reported Physical Activity Change in Patients With Physical Disabilities Hospitalized for Rehabilitation in A Physical Medicine and Rehabilitation Clinic

Start date: March 1, 2020
Phase:
Study type: Observational

Disability was defined by WHOas a restriction or lack of ability to perform daily activity, but this definition was later changedto problems in functioning in the WHO classification of Functioning, Disability and Health (ICF). Osteoarthritis, back pain, neck pain, rheumatologic diseases, neurologic disorders (stroke, spinal cord injury, multiple sclerosis, Parkinson diseases) can cause physical disabilities.Recent studies have shown that; high levels ofdisability is related with low levels of physical activity.Individuals with disability are commonly hospitalized ininpatients clinicsfor rehabilitation, which aims to achieveoptimal functional level ofpatients within their own limitations.A rehabilitation program can be an excellent opportunity to integrate post-rehabilitation physical activity into their lifestyle.This study aimed to examine the short term effect of inpatient rehabilitation program on self -reported physical activity both participants with physical disabilities due to musculoskeletal, and neurological disorders

NCT ID: NCT04799093 Completed - Impairment Clinical Trials

Eye Movement Tracking to Detect Impairment Due to Acute Cannabis Intoxication

Start date: February 1, 2021
Phase:
Study type: Observational

The purpose of this study is to determine the accuracy of an impairment algorithm based on eye tracking while watching a short film clip, in comparison to a clinical reference standard of impairment.

NCT ID: NCT03680365 Completed - Clinical trials for Duchenne Muscular Dystrophy

Your Voice; Impact of Duchenne Muscular Dystrophy (DMD) on the Lives of Families

Start date: September 20, 2018
Phase:
Study type: Observational

The purpose of this study is to improve the understanding of the treatment goals that a person with Duchenne Muscular Dystrophy (DMD) or the caregiver may be most interested in, based on the severity of the person's disease. Data will be collected by online survey when the participant accepts the study invitation ("RSVP questionnaire") and telephone interview on the functional burden and self-identified treatment goals from the perspective of people with DMD and their caregivers. Interviews will be analyzed to help identify things important to Duchenne families to measure in clinical trials and to inform the selection of key concepts of interest and development of future clinical outcome measures, including observer reported outcomes/patient reported outcomes. The study will be conducted in the United States and will enroll between 45 and 120 participants 11 years or older living with DMD as well as their caregivers. The time commitment for the online survey and the telephone interview is about one hour. It is anticipated that the entire study will be completed within one year.

NCT ID: NCT03270592 Completed - Diabetes Clinical Trials

Assessment of Service and Hearing Dogs

Start date: September 17, 2009
Phase: N/A
Study type: Interventional

For persons with impairments and certain illnesses the use of service dogs may have positive effect. The effects of using these dogs to assist in every day life need to be studied further.The aim of the study was to assess how health care consumption was effected by using certified service dogs and to study the cost-effectiveness of having a certified service dog.

NCT ID: NCT02971072 Completed - Pain Clinical Trials

Neurophysiology of Weakness and Exercise in Rotator Cuff Tendinopathy

Start date: July 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to examine deficits in activation and motor patterns, as well as central drive in patients with rotator cuff tendinopathy. There are three specific aims: (1) determine the effect of acute pain relief on rotator cuff muscle activation in patients with rotator cuff tendinopathy, (2) determine the effect of exercise on rotator cuff muscle activation in patients with rotator cuff tendinopathy, and (3) compare rotator cuff muscle activation between patients with rotator cuff tendinopathy and healthy controls.

NCT ID: NCT00559819 Completed - Impairment Clinical Trials

Validation of Driving Simulator to Blood Alcohol Concentration Standards for Impaired Driving

ALCDrive
Start date: February 2008
Phase: Phase 3
Study type: Interventional

The proposed study will validate and determine sensitivity of our new driving simulator, created to evaluate driving ability in a related study to show similar driving performance between patients on chronic opioid treatment and a control group. Although the commercial version of the simulator has been validated for certain populations and certain measures, these require re-calibration for our own clinical study. The investigators propose a prospective randomized clinical trial to evaluate driving skills under alcohol consumption using a driving simulator. Two groups of study subjects will be utilized, with the majority (80%) receiving alcohol and placebo at different times. A smaller set of study subjects (20%) will be given placebo on both trials to evaluate learning effects and placebo blinding effectiveness. Each group will take the driving test at three time points: once as a baseline at the beginning of the study, once after the 1st dosing of the placebo and again after dosing two of the alcohol or placebo beverage. This information will allow us to evaluate driving ability under other potentially impairing conditions such as opioid usage.