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NCT ID: NCT06280690 Recruiting - Colorectal Cancer Clinical Trials

SGM-101 Tumor Targeted Fluorescence Endoscopy in Rectal Polyps With Suspected T1 Adenocarcinoma or High Grade Dysplasia

SGM-T1
Start date: January 31, 2024
Phase: Phase 2
Study type: Interventional

This will be the first trial investigating whether tumor targeted fluorescence is able to discriminate invasive T1 carcinoma / High grade dysplasia from Low grade dysplasia/normal tissue during endoscopic intraluminal resection. This will be done using the CEA-targeted fluorescent probe SGM-101.

NCT ID: NCT06182683 Recruiting - Clinical trials for Coronary Artery Disease

Concurrent OCT and FFR-guided PCI in CAD

OPTICARE-CAD
Start date: November 30, 2023
Phase: N/A
Study type: Interventional

The present study is a prospective randomized clinical trial aimed to compare the therapeutic strategy of angiography-guided versus concurrent OCT/FFR-guided intervention in patients with coronary artery disease.

NCT ID: NCT06127810 Not yet recruiting - Image Clinical Trials

MRI Gadopiclenol Enhanced Imaging of CNS Tumors

Start date: June 1, 2024
Phase:
Study type: Observational

The purpose of this pilot study is to compare a standard of care MRI scan to a non-standard of care MR imaging with portable (0.064 Tesla) MRI following the administration of non-SOC contrast called Gadopiclenol on 10 subjects with known brain tumors. Participants will be randomized to receive either standard MRI or portable MRI first following contrast injection

NCT ID: NCT06097741 Not yet recruiting - Image Clinical Trials

Pulmonary MRI Using Ultra Short /Zero TE Sequences

Start date: November 1, 2023
Phase: N/A
Study type: Interventional

Modern imaging modalities, especially magnetic resonance imaging (MRI) have greatly advanced in recent years. Through technical advances, proton-based magnetic resonance imaging (MRI) has steadily increased in use to assess pulmonary structures in the pediatric population especially in Europe. Such technical developments have advanced by overcoming rapid decaying of transverse relaxation time and cardiac/chest movement synchronization, showing MRI to be feasible with respect to morphological and functional assessment of pulmonary impairment, in chronic lung disease such as cystic fibrosis for disease progression and prediction of exacerbation. However pulmonary imaging with MRI has also been feasible to detect pulmonary nodules in malignancies (allowing for spatial resolution).

NCT ID: NCT06056531 Completed - Clinical trials for Knowledge, Attitudes, Practice

Peripheral Intravenous Cannulation Using Three Different Techniques on Nursing Students

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

Aim: The primary objective was to assess the effect of three different teaching techniques on the success of first-time peripheral intravenous cannulation (PVC) insertion as well as the vein prominence of nursing students. As a secondary objective, the authors conducted research on the students' PVC knowledge levels and skills performance, in the PVC procedure and the duration of the procedure, their satisfaction, and self-confidence in learning. Design: A randomized controlled trial with a pretest and posttest was conducted between February and July 2022, with near-infrared light visualization (n=49), isometric exercise (n=50), and each other's arms (n=48) with nursing students in Turkey.

NCT ID: NCT06035250 Recruiting - Gastric Cancer Clinical Trials

AI Prediction of Gastric Cancer Response to Neoadjuvant Chemotherapy

Start date: September 10, 2023
Phase:
Study type: Observational

This study seeks to develop a deep-learning-based intelligent predictive model for the efficacy of neoadjuvant chemotherapy in gastric cancer patients. By utilizing the patients' CT imaging data, biopsy pathology images, and clinical information, the intelligent model will predict the post-neoadjuvant chemotherapy efficacy and prognosis, offering assistance in personalized treatment decisions for gastric cancer patients.

NCT ID: NCT06017193 Not yet recruiting - Alveolar Bone Loss Clinical Trials

Ultrasound for Socket Healing Evaluation

Start date: June 1, 2024
Phase:
Study type: Observational

The design is a single blinded, dual comparative study of ultrasound versus micro-CT/LASCA in one study group. Up to a total of 140 subjects registered will be recruited. Subjects who are treatment planned for extraction of a hopeless tooth and socket augmentation with bone graft and are planned for a dental implant surgery. The socket will be evaluated before the extraction and multi-time points during healing until an implant is placed with various evaluation tools, including ultrasound.

NCT ID: NCT05965817 Recruiting - Colorectal Cancer Clinical Trials

Fluorescence-guided Resection Of Colorectal Liver Metastases Using SGM-101 and Indocyanine GREEN

FOCUS GREEN
Start date: December 1, 2023
Phase: Phase 2
Study type: Interventional

This will be the first trial testing the feasibility of working simultaneously with the two fluorescent dyes ICG and SGM-101 in 10 patients with colorectal metastases.

NCT ID: NCT05848934 Not yet recruiting - Clinical trials for Coronary Heart Disease

Research on the Relationship Between Cognitive Function Changes and Cerebrovascular Health in Patients With Coronary Heart Disease

Start date: May 1, 2023
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to elucidate the imaging mechanisms of cognitive function changes in patients with coronary heart disease before and after surgery or conservative treatment, and to evaluate and predict the postoperative neurological function recovery and cerebrovascular health level of patients by combining serum markers and patient cardiovascular health evaluation indicators.

NCT ID: NCT05848921 Not yet recruiting - Clinical trials for Carotid Artery Stenosis

Evaluation of Brain Health and Surgical Efficacy in Patients With Carotid Artery Stenosis

Start date: May 1, 2023
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to explore the relationship between the recovery of cerebrovascular morphology and cognitive function before and after surgical treatment in patients with carotid artery stenosis and their preoperative cardiac health status. And combined with preoperative cognitive status, serum markers, and cardiovascular health evaluation indicators, evaluate and predict the possibility of postoperative neurodegenerative diseases and the level of cerebrovascular health in patients.