Clinical Trials Logo

Ileus clinical trials

View clinical trials related to Ileus.

Filter by:

NCT ID: NCT03505476 Recruiting - Ileus Clinical Trials

Optimizing the Previs Device for Prediction of Postoperative Ileus

Start date: April 24, 2018
Phase: N/A
Study type: Interventional

The research proposed in this study will develop a noninvasive prototype device that will capture intestinal sounds, process signals, and display predictive information in real-time at the point-of-care using algorithms already developed at this institution.

NCT ID: NCT03386136 Completed - Ileus Clinical Trials

Therapeutic Oxygen for Gastrointestinal Atony (TOGA)

TOGA
Start date: January 25, 2018
Phase: Phase 1
Study type: Interventional

This study is a non invasive study to see if 100% oxygen therapy will help to resolve an intestinal obstruction.

NCT ID: NCT03352414 Terminated - Ileus Clinical Trials

Phase 2 RCT of Alvimopan vs. Placebo After CRS/HIPEC

ILEUS
Start date: March 8, 2018
Phase: Phase 2
Study type: Interventional

The purpose of this study is to investigate the ability of alvimopan to reduce the time to return of bowel function in patients undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Half of the participants will receive alvimopan or and half will receive placebo immediately before and for up to seven days after surgery.

NCT ID: NCT03261518 Not yet recruiting - Clinical trials for Contrast-induced Nephropathy

Investigation of Relationship Between Contrast Nephropathy and Caval Index Measurement in Patients With Ileus in ED

Start date: August 24, 2017
Phase: N/A
Study type: Observational

In this study, the investigators aimed to evaluate the incidence of vena cava inferior diamater on ultrasound guidance of intravascular volume before diagnosis of contrast - enhanced CT for diagnostic purposes in ileus patients and to investigate the incidence and risk of developing contrast nephropathy due to contrast - enhanced CT.

NCT ID: NCT03222557 Recruiting - Rectal Cancer Clinical Trials

Electroacupuncture for Postoperative Ileus After Laparoscopic Surgery for Mid and Low Rectal Cancer

Start date: November 2017
Phase: N/A
Study type: Interventional

This is a prospective, randomized, sham-controlled, superiority trial that aimed to investigate the efficacy of electroacupuncture (EA) in reducing the duration of postoperative ileus and hospital stay after laparoscopic total mesorectal excision or abdominoperineal resection for rectal cancer.

NCT ID: NCT03176316 Recruiting - Ileus Clinical Trials

The Use of Oral Naloxone to Prevent Post Spinal Fusion Ileus

FusionIleus
Start date: January 2, 2018
Phase: Phase 4
Study type: Interventional

Postoperative ileus and opioid induced constipation are well-known post-operative complications. Previously, research has shown that using peripherally acting opioid antagonists can help alleviate the condition. There has not been a prospective study to investigate whether use of peripherally acting opioid antagonists are effective in preventing post-operative ileus in patients having spinal fusion surgeries.

NCT ID: NCT03097900 Completed - Postoperative Ileus Clinical Trials

Does Caffeine Enhance Bowel Recovery After Colorectal Surgery?

Start date: November 2, 2017
Phase: Phase 2
Study type: Interventional

Postoperative ileus is a frequently occurring surgical complication. It is defined as temporary inhibition of propulsive bowel activity and is manifested by abdominal distention, nausea, vomiting and diet intolerance. It may lead to a prolonged hospital stay, hospital-acquired infections or complications that may require additional treatments (e.g. analgesia, fluids, electrolyte replacement, nasogastric tube decompression), and as a result increase medical costs. Previous studies showed that postoperative coffee consumption shortens the time to first bowel movement after colorectal resections. However, none could explain the mechanism by which coffee stimulates intestinal motility and the determinant agent for this action is still up for discussion (either caffeine or another coffee component). Coffee has a negligible caloric content; It has a pH that varies from 5 to 6 (less acidity than other beverages that have no similar effect on bowel motility) and it is hypotonic. Therefore, it is highly unlikely that bowel motility is due to the physical properties of the coffee. Much more likely, that one (or more) of the numerous phytochemicals of the coffee bean are responsible for this effect, when the most obvious candidate seems to be caffeine. However, as mentioned above, very little evidence exists that caffeine was responsible for the observed effect on colonic function in previous studies. The purpose of this single-centered, prospective, single blinded, randomized clinical trial is to evaluate whether the use of caffeine in the post-operative period significantly reduces the duration of postoperative ileus, and therefore, improves recovery and shorten the hospital stay. The study hypothesis is that post-operative use of caffeine will reduce time to recovery of GI function (post-operative ileus) by at least 15 hours and thus reduce hospital length of stay by at least 15 hours in patients undergoing elective colorectal operations. 50 patients due to undergo large bowel resection via laparotomy or laparoscopy will be enrolled and randomized (1:1) to those who will receive caffeine (100 mg 3 times per day) and those who will receive placebo (tap water) starting on the morning of postoperative day 1 after surgery until flatus will occur for the first time or to a maximal period time of 7 days, whichever comes earlier.

NCT ID: NCT03068975 Terminated - Clinical trials for Post Operative Ileus

Alvimopan Use in Polytraumatized Patients

Start date: September 1, 2017
Phase: Phase 4
Study type: Interventional

To evaluate the efficacy and safety of Alvimopan(12 mg) in recovery of bowel function in an emergency trauma setting without the pre-operative dosage in patients that will receive abdominal surgery.

NCT ID: NCT03041675 Recruiting - Paralytic Ileus Clinical Trials

Effects of Laser Acupuncture Therapy on Paralytic Ileus

Start date: February 13, 2017
Phase: N/A
Study type: Interventional

Ileus occurs from hypomotility of the gastrointestinal tract. Causes of Paralytic ileus include post-operation, stroke, and bed-ridden for a long time. Medicine treatment is less and less effective over time. Some study revealed that Moxibustion and Acupuncture are effective in Paralytic ileus. Investigators try to find other treatment except of medicine. Laser Acupuncture is a safe and non-invasive choice. This study is to evaluate effect of Laser Acupuncture on Paralytic ileus.

NCT ID: NCT02958566 Recruiting - Pain, Postoperative Clinical Trials

Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery

Start date: January 2017
Phase: Phase 4
Study type: Interventional

The General Objective of this study is to investigate the cost and efficacy of treating patients undergoing colorectal surgical resections with an opioid limited pain control regimen as part of an Enhanced Recovery After Surgery (ERAS) Protocol. This group will be compared to a traditional opioid based pain control regimen.