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Ileus clinical trials

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NCT ID: NCT06338813 Completed - Ileus Clinical Trials

Digital Manometry for Intra-Abdominal Pressure Measurement in Ileus

Start date: October 30, 2022
Phase: N/A
Study type: Interventional

Although many measurement techniques have been tried for intra-abdominal pressure, the Kron technique is currently the gold standard method. However, the search for other methods continues due to its long application time, the need for more equipment, and impracticality. Consequently, the investigators sought to investigate a quicker and more accessible method suitable for successful intra-abdominal pressure measurement in the emergency department. This study aimed to compare intra-abdominal pressure measurements in patients diagnosed with ileus using a digital manometer and the Kron Technique.

NCT ID: NCT06320548 Completed - Clinical trials for Cesarean Section Complications

The Efficacy of Preoperative Low-residue Diet on Postoperative Ileus Following Cesarean Section

Start date: October 1, 2018
Phase: N/A
Study type: Interventional

The aim of the present study was to evaluate the efficacy of preoperative low-residue diet on postoperative ileus in women undergoing elective cesarean section. It is a surgeon-blind, randomized controlled trial enrolling pregnant women at ≥39 weeks of gestation undergoing elective cesarean section. Patients were preoperatively randomized to receive either low-residue diet (arm A) or free diet (arm B) starting from three days before surgery. The primary outcome was the postoperative ileus at 24 hours after surgery. The secondary outcomes were the postoperative pain (assessed through VAS scale), the quality of the surgical field (scored using a 5-point scale, from poor to excellent), postoperative complications, and the length of hospital stay. Perioperative data were collected and compared between groups.

NCT ID: NCT06018961 Not yet recruiting - Colorectal Surgery Clinical Trials

Study of Postoperative Ileus in Digestive Surgery

IPCID
Start date: November 15, 2023
Phase:
Study type: Observational

Post-operative ileus is a temporary stoppage of bowel function following surgery. Indeed it can occur in 20% of cases during post-operative follow-up of bowel surgery. The absence of resumption of transit can lead to the implementation of specific treatments such as the placement of a nasogastric tube and drug treatments. To date, the definition of this event is not accepted by everyone and is not based on reproducible evaluation criteria. The main objective of this study is to evaluate a score used to date to define postoperative ileus, the IFEED score, and to compare it to the length of postoperative stay.

NCT ID: NCT05985343 Recruiting - Ileus Clinical Trials

The Impact of Sugammadex on Ileus After Abdominal Wall Reconstruction

Start date: January 15, 2024
Phase: Phase 4
Study type: Interventional

The aim of the study is to determine if the usage of sugammadex would reduce the time to return of bowel function when compared to standard of care (neostigmine/glycopyrrolate) when used for neuromuscular blockade reversal in patients with open abdominal wall reconstruction (AWR).

NCT ID: NCT05753709 Completed - Ileus Clinical Trials

Conventional Hand Sewn End-To-End Anastomosis Versus Side-To-Side Anastomosis for Stoma Reversal: A Prospective Study

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare approaches to enterostomy reversal by hand-sewn end-to-end anastomosis versus side-to-side anastomosis (sub-divided into hand-sewn side-to-side anastomosis and stapled side-to-side anastomosis). The main question it aims to answer is: • If either of the approaches are better than the other with respect to success rates, efficacy, post-operative complications and overall morbidity. Participants admitted for stoma reversal will be divided into two groups: 1. EE: Conventional Hand-sewn end-to-end anastomosis, and 2. SS: Side-to-side anastomosis, which will be further divided into 2 sub-groups: 1. HSSA: Hand-sewn side-to-side anastomosis 2. SSSA: Stapled side-to-side anastomosis Researchers will compare the EE group to SS group overall, and a second comparison will be made between EE, HSSA and SSSA groups, to see: 1. Rates of major post-operative complications 2. Rates of short-term complications (within 30 days of surgery) 3. Rates of re-operation 4. Post-operative length of stay in the hospital

NCT ID: NCT05752071 Recruiting - Postoperative Ileus Clinical Trials

Gastrointestinal Stimulation as a Treatment of Postoperative Ileus Following Extensive Surgery

STIMULATE
Start date: April 1, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to investigate the effect of gastrointestinal stimulation with a pacemaker on the length of postoperative bowel paralysis in patients undergoing major abdominal surgery due to metastasizing colorectal cancer, appendiceal cancer or pseudomyxoma peritonei. The main question it aims to answer is if the length of postoperative ileus is reduced when the gastrointestinal tract is stimulated with a pacemaker. All participants will undergo cytoreductive surgery +/- heated intraperitoneal chemotherapy (the standard treatment for colorectal cancer, appendiceal cancer with peritoneal carcinomatosis or pseudomyxoma peritonei). After surgery, but before the abdomen is closed a pace lead will be attached to the stomach, exteriorized trough the abdominal wall and connected to an external pacemaker. The pacemaker is either turned on (experimental group) or turned off (control group). Furthermore, the patients are asked to ingest a SmartPill capsule two hours prior to surgery. This will transmit information on gastrointestinal transit times and motility. After surgery, patients will be asked to fill out a diary on bowel movements once a day.

NCT ID: NCT05712525 Recruiting - Clinical trials for Gastrointestinal Diseases

Gut Recovery In Patients Following Surgery

GRIPS
Start date: October 7, 2022
Phase:
Study type: Observational

The purpose of the study is to determine if the myoelectrical measurements made by the G-Tech Wireless Patch System correlate with clinical markers of postoperative recovery such as passage of flatus/bowel movement, oral tolerance of diet and discharge readiness. Subsequently the data will be studied to establish which information in the signals is important in determining when to feed patients and possibly discharge them..

NCT ID: NCT05669781 Completed - Ileus Postoperative Clinical Trials

The Effects of Combined Gum-chewing and Parenteral Metoclopramide on Post-operative Ileus

Start date: October 1, 2018
Phase: Phase 4
Study type: Interventional

A delay in the return of bowel function is a common occurrence after abdominal surgeries.1 The goal of this study was to test the effect of the combined use of chewing a gum and administering metoclopramide intravenously on the duration of this natural delay in the return of bowel function after abdominal surgeries. Patients were grouped into four: the first group received both gum and metoclopramide; the second group received only gum; the third group received only metoclopramide, while the fourth group (the control group) received sterile water for injection. The groups were compared for the time taken for bowel function to return and the duration of hospital stay.

NCT ID: NCT05654649 Recruiting - Postoperative Ileus Clinical Trials

Dexamethasone in the Prevention of Post-spinal Paralytic Ileus After Cesarean Section

Start date: December 1, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

Postoperative ileus is a perplexing problem for clinical surgeons. It occurs not only after abdominal surgery but also after any surgery that requires general anesthesia. Postoperative ileus is defined as the dysfunction of gastrointestinal motility after surgery, characterized by a decrease in, or stagnation of, intestinal peristalsis.

NCT ID: NCT05512741 Recruiting - Postoperative Ileus Clinical Trials

Intestinal Microbiota and Postoperative Ileus After Colorectal Surgery

MICRO-IPO
Start date: October 21, 2022
Phase:
Study type: Observational [Patient Registry]

Postoperative ileus (POI) after colorectal surgery is frequent and is a burden for national health authority because it increases the morbidity and the length of hospital stay. Some of the stage of the mechanism of POI are known and are now targeted to reduce its occurence but despite these measures, POI still happens in 10-30% of surgeries. The role of the intestinal microbiota in POI is unknown while it could be a new target to reduce its duration or its occurence.