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Ileus clinical trials

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NCT ID: NCT04090073 Recruiting - Postoperative Ileus Clinical Trials

Electroacupuncture Combined With Fast-track Perioperative Program for Laparoscopic Colorectal Surgery

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

Background: The investigators' previous study demonstrated that electroacupuncture (EA) reduces the duration of postoperative ileus and hospital stay after laparoscopic colorectal surgery within a traditional perioperative care setting. Recent evidence also suggested that a 'fast-track' (FT) perioperative program may help accelerate recovery after colorectal surgery. It is uncertain whether the combination of EA and FT program will result in faster recovery after laparoscopic colorectal surgery when compared with FT program alone. Objectives: To compare the efficacy of EA combined with FT program versus FT program alone in reducing the duration of postoperative ileus and hospital stay after laparoscopic colorectal surgery Design: Prospective randomized trial. Subjects: 72 consecutive patients undergoing elective laparoscopic resection of colonic and upper rectal cancer without conversion will be recruited. Interventions: Patients will be randomly allocated to one of the two groups receiving either EA + FT program, or FT program alone. Outcome measures: Primary outcome: time to defecation. Secondary outcomes: duration of hospital stay, time to resume diet, pain scores, analgesic requirement, morbidity, quality of life, and medical costs. Conclusions: This study serves as a good example that illustrates an integrated approach in combining Chinese and Western models of health care. It will provide evidence-based clarification of the role of EA in enhancing recovery after laparoscopic colorectal surgery within a FT perioperative care setting. As laparoscopic colorectal surgery has been shown to have a higher direct cost than the open counterpart, a faster postoperative recovery may help reduce the financial burden to the hospital/healthcare system.

NCT ID: NCT04009954 Recruiting - Clinical trials for Post-operative Ileus

Post-operative Ileus and Gut Microbiota

Start date: April 1, 2019
Phase:
Study type: Observational

Postoperative ileus (POI) is a common clinical condition after abdominal surgical procedure, leading to increased patient morbidity and prolonged hospitalisation.The mechanism of POI is not very clear until now. At the end of the 20th century, the inflammatory-mediated ileus hypothesis was introduced. But the initial trigger of the inflammatory cascade is unclear.Previous study demonstrate a clear association between colonic transit time, gut microbiota composition and urinary metabolic phenotype. Here the investigators suggest that the perioperative gut microbiota may contribute to POI.

NCT ID: NCT03666377 Recruiting - Bowel Ileus Clinical Trials

Chewing Gum on Postoperative Ileus in Children

GUM_1
Start date: December 1, 2018
Phase: N/A
Study type: Interventional

Traditional postoperative care has been challenged recently to improve and speedup recovery (including the return of bowel function) such that patients can be discharged to home more quickly. This approach includes earlier mobilization of the patient, and introducing solid food sooner. Additionally, there is evidence in adults to suggest that "sham feeding" by chewing gum may also speed up bowel recovery so the patient may tolerate a solid diet earlier. The aim of this study is to determine if gum chewing can enhance bowel recovery in children who undergo abdominal surgery.

NCT ID: NCT03505476 Recruiting - Ileus Clinical Trials

Optimizing the Previs Device for Prediction of Postoperative Ileus

Start date: April 24, 2018
Phase: N/A
Study type: Interventional

The research proposed in this study will develop a noninvasive prototype device that will capture intestinal sounds, process signals, and display predictive information in real-time at the point-of-care using algorithms already developed at this institution.

NCT ID: NCT03222557 Recruiting - Rectal Cancer Clinical Trials

Electroacupuncture for Postoperative Ileus After Laparoscopic Surgery for Mid and Low Rectal Cancer

Start date: November 2017
Phase: N/A
Study type: Interventional

This is a prospective, randomized, sham-controlled, superiority trial that aimed to investigate the efficacy of electroacupuncture (EA) in reducing the duration of postoperative ileus and hospital stay after laparoscopic total mesorectal excision or abdominoperineal resection for rectal cancer.

NCT ID: NCT03176316 Recruiting - Ileus Clinical Trials

The Use of Oral Naloxone to Prevent Post Spinal Fusion Ileus

FusionIleus
Start date: January 2, 2018
Phase: Phase 4
Study type: Interventional

Postoperative ileus and opioid induced constipation are well-known post-operative complications. Previously, research has shown that using peripherally acting opioid antagonists can help alleviate the condition. There has not been a prospective study to investigate whether use of peripherally acting opioid antagonists are effective in preventing post-operative ileus in patients having spinal fusion surgeries.

NCT ID: NCT03041675 Recruiting - Paralytic Ileus Clinical Trials

Effects of Laser Acupuncture Therapy on Paralytic Ileus

Start date: February 13, 2017
Phase: N/A
Study type: Interventional

Ileus occurs from hypomotility of the gastrointestinal tract. Causes of Paralytic ileus include post-operation, stroke, and bed-ridden for a long time. Medicine treatment is less and less effective over time. Some study revealed that Moxibustion and Acupuncture are effective in Paralytic ileus. Investigators try to find other treatment except of medicine. Laser Acupuncture is a safe and non-invasive choice. This study is to evaluate effect of Laser Acupuncture on Paralytic ileus.

NCT ID: NCT02958566 Recruiting - Pain, Postoperative Clinical Trials

Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery

Start date: January 2017
Phase: Phase 4
Study type: Interventional

The General Objective of this study is to investigate the cost and efficacy of treating patients undergoing colorectal surgical resections with an opioid limited pain control regimen as part of an Enhanced Recovery After Surgery (ERAS) Protocol. This group will be compared to a traditional opioid based pain control regimen.

NCT ID: NCT02847364 Recruiting - Ileus Clinical Trials

Effect of Chewing Gum on Post-operative Ileus (GUMPI)

GUMPI
Start date: February 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether chewing gum post-operatively decreases the time to first flatus or defecation in patients undergoing spine surgery as a indirect indicator of post-operative ileus.

NCT ID: NCT02673671 Recruiting - Clinical trials for Post-operative Ileus

G-Tech Feasibility Study for Early Detection of a Post-op Ileus

GTECHPOI
Start date: February 2016
Phase:
Study type: Observational

This feasibility study is for the purpose of determining if the G-Tech Device can differentiate between normal return of GI activity post-operatively and the myoelectric activity in patients who develop a POI.