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Hypoxia clinical trials

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NCT ID: NCT06373562 Completed - Hypoxia Clinical Trials

Effect of Hypoxic Exposure on Blood Variables in Elite Wrestlers

Start date: December 2, 2013
Phase: N/A
Study type: Interventional

Twelve male wrestlers of the National Polish Team were observed in the study during the camp. The hypoxia group (n=6) participated in sports training and hypoxic exposure, while the control group (n=6) included wrestlers participating only in sports training. The hypoxic group lived and slept in hypoxic rooms. During the camp, all wrestlers followed the same training schedule and diet. In the blood were determined levels of creatine kinase (CK), C-reactive protein (hsCRP) concentration, nitric oxide (NO), morphology, reticulocytes, lipid profile, and ferritin. Also vascular endothelial growth factor (VEGF, VEGFR2, and VEGFR3), erythropoietin (EPO), angiopoietin (Ang 1, Ang 2), endothelial cell adhesion factor-1 (VCAM-1), Erythropoietin (EPO) and hypoxia-inducible factor 1 (HIF-1). Body weight composition was determined.

NCT ID: NCT06371651 Completed - Oxygen Deficiency Clinical Trials

Creatine and GAA for Brain Oxygenation

CREGAA-OXY
Start date: March 1, 2024
Phase: N/A
Study type: Interventional

The main aim of this randomized controlled trial is to evaluate cerebral blood oxygenation after 7-day administration of a creatine-guanidinoacetic acid (GAA) mixture in healthy adults before, during, and after a series of cognitive tests.

NCT ID: NCT06344286 Completed - Clinical trials for Hypoxic-Ischemic Encephalopathy

The Effects of Minimal Enteral Nutrition on Mesenteric Blood Flow and Oxygenation in Neonates With HIE

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the effects of minimal enteral nutrition (MEN) on mesenteric blood flow and oxygenation with Doppler USG and Near Infrared Spectroscopy (NIRS) during therapeutic hypo¬thermia (TH) in babies with hypoxic ischemic encephalopathy. The main question it aims to answer is: 1- How do the mesenteric blood flow and oxygenation get affected with MEN during TH? Participants will be either fed with MEN during TH or given placebo.

NCT ID: NCT06306950 Completed - Clinical trials for Severe Traumatic Brain Injury

Prioritization of Cerebral Deoxygenation in Severe Traumatic Brain Injury and Mortality Benefit.

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

Severe traumatic brain injury with a decrease in cerebral oximetry is associated with multiple impaired systemic microcirculations, more morbidities, and a higher mortality rate. When using the brain as an index organ, interventions to improve brain oxygen delivery may have systemic benefits for these patients.

NCT ID: NCT06264193 Completed - Hypoxia Clinical Trials

The Impact of Hypoxia on the Biochemical and Morphological Parameters of Blood in Rowers.

IHOBMPBR
Start date: November 30, 2014
Phase: N/A
Study type: Interventional

The response to hypoxia is very individual and epending on many aspects, such as the type of training, duration, intensity, or hypoxic stimulus, hypoxia affects the athlete in various ways. The results of this study have shown that 18 days of the LH-TL method does not significantly increase the level of EPO and VEGF in rowers. However, reticulocytes, immature red blood cells, have shown significant differences after 18-d LH-TL between groups. Further research should be carried out to investigate an optimal hypoxic dose and time, which will raise EPO, VEGF, and morphology variables.

NCT ID: NCT06149416 Completed - Healthy Clinical Trials

SpO2 Accuracy of Noninvasive Pulse Oximeter Sensor With Motion Conditions

Start date: May 27, 2023
Phase: N/A
Study type: Interventional

The purpose of this clinical study is to validate the SpO2 accuracy of the Stryker Sustainability Solutions pulse oximetry sensors during motion conditions over the range of 70 -100% SaO2 as compared to arterial blood samples assessed by CO-Oximetry during conditions in which the subject is moving. The end goal is to provide supporting documentation for the SpO2 accuracy validation of the reprocessed sensors with motion indications.

NCT ID: NCT06101654 Completed - Hypoxia Clinical Trials

Accuracy of Evie Ring Pulse Oximeter in Profound Hypoxia

Start date: January 9, 2024
Phase:
Study type: Observational [Patient Registry]

The goal of this study was to evaluate the accuracy of pulse oximeters over the range of 70-100% per ISO 80601-2-61:2019. Four devices were placed on each subject with two on each index finger at the base and two on each index finger at the fingertip. SpO2 measurements from these devices were compared to sampling of arterial blood during brief stable oxygen desaturation in healthy volunteers to evaluate the claimed range.

NCT ID: NCT06060093 Completed - Sleep Clinical Trials

Effect of Ketone Ester Supplementation on Sleep and Recovery in Hypoxia

Start date: February 20, 2023
Phase: N/A
Study type: Interventional

This study specifically aims to elucidate the effects of IEK on sleep and recuperation in hypoxia, after training in normoxia. These conditions are in line with the widely applied live-high train-low strategy. Moreover, blood and tissue oxygenation status, as well as cerebral blood flow and cognitive function will be assessed.

NCT ID: NCT06054022 Completed - Atelectasis Clinical Trials

Usage of High Flow Nasal Cannula in Preventing Desaturations in Elderly Patients Going for Lower Limb Surgeries

Start date: July 7, 2020
Phase: N/A
Study type: Interventional

To study the effect of high flow nasal cannula in comparisons with nasoprong used intraoperatively in patients oxygenation status

NCT ID: NCT06016998 Completed - Clinical trials for Hypoxemia During Surgery

Prediction Model of Hypoxemia in Gastrointestinal Endoscopy Sedation

Start date: September 1, 2023
Phase:
Study type: Observational

The incidence of hypoxemia during gastrointestinal endoscopy sedation is high, but there is still a lack of perfect prediction model of hypoxemia, which often leads to unpredictable respiratory complications. In order to ensure the safety of gastrointestinal endoscopy sedation and make emergency plans in advance, a better diagnostic model is urgently needed to help assess the risk of hypoxemia in patients undergoing the process and make early intervention measures. Facial photography is a simple and feasible measure that can show the facial soft tissue and structure of bone. The purpose of this study is to explore whether facial photography combined with other clinical indicators can build a prediction model of hypoxemia during gastrointestinal endoscopy sedation.