Hypoxia, Altitude Clinical Trial
Official title:
Effects of Physical Training in Altered Environmental Conditions (in a Hypoxic Thermoclimatic Chamber) on Exercise Capacity and Selected Physiological Responses of the Human Body
The main objective of the study is to evaluate the physiological-biochemical effects of physical training under artificially altered climatic conditions (using a hypoxic thermoclimatic chamber) in particular to determine the effect of such training on exercise capacity and physiological response, including the effect of training in high-performance athletes. The study will evaluate the effects of physical training and the simultaneous application of hypoxia and heat/cold on aerobic and anaerobic capacity and the physiological response of the human body. The aim of the study is to find the most favourable environmental conditions for physical training in order to maximise physical performance.
Status | Recruiting |
Enrollment | 128 |
Est. completion date | December 31, 2025 |
Est. primary completion date | December 31, 2024 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Male |
Age group | 18 Years to 35 Years |
Eligibility | Inclusion Criteria: absence of medical contraindications to high-intensity physical exertion. The medical examination is required (included an exercise ECG, blood tests to exclude anemia or low hemoglobin and iron concentration) Exclusion Criteria: any training (including hypoxia training or exposure) performed in the 6 months prior to the beginning of the intervention |
Country | Name | City | State |
---|---|---|---|
Poland | University School of Physical Education in Cracow | Kraków |
Lead Sponsor | Collaborator |
---|---|
University School of Physical Education, Krakow, Poland |
Poland,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Measurement of aerobic capacity (endurance) | Measurement of maximal oxygen uptake and determination of ventilatory thresholds (ergospirometry) | 7 days before training and 7-10 days after the training. Training will last 4 weeks. | |
Primary | Measurement of anaerobic capacity | Measurement of maximal anaerobic power (Wingate Anaerobic Test) | 7 days before training and 7-10 days after the training. Training will last 4 weeks. | |
Primary | Blood analysis | indicators of muscle damage, inflammatory markers (interleukins), oxidative stress, lactate concentration, tissue oxygenation, selected hormones (including erythropoietin) and enzymes, HIF (hypoxia inducible factor), selected vitamins, morphology (including reticulocytes), rheology and blood biochemistry | Before (10 min) and after (3 min) the first and last training. The training will last 4 weeks and will consist of 12 workouts |
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