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Hypotension clinical trials

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NCT ID: NCT03938480 Completed - Hypotension Clinical Trials

Duration Threstholds of Intraoperative Hypotension

Start date: January 1, 2019
Phase:
Study type: Observational

Intraoperative hypotension is common in non cardiac surgery. longer duration of intraoperative hypotension is related with postoperative morbidity and mortality. however, with the change of hypotension criteria, the duration threshold also change. the relationship of different hypotension criteria and its duration is unclear. This study is to explore the their relationship.

NCT ID: NCT03927066 Completed - Clinical trials for Hypotension and Shock

Physiological Validation of Current Machine Learning Models for Hemodynamic Instability in Humans

Start date: May 12, 2021
Phase: N/A
Study type: Interventional

This study will be collecting data on participants undergoing lower body negative pressure (LBNP) to simulate progressive blood loss. The goal of the study is to collect data to allow for development of an algorithm with machine learning to predict blood pressure responses to hyporvolemia by analyzing the arterial waveforms collected during LBNP.

NCT ID: NCT03916861 Completed - Renal Insufficiency Clinical Trials

BIA Versus Physician Adjustment in Acute Kidney Injury Patients Requiring Renal Replacement Therapy

Start date: October 1, 2017
Phase: N/A
Study type: Interventional

This study was designed to compare the efficacy of BIA and physician adjustment to prevent intradialytic hypotension in patients with acute kidney injury who received renal replacement therapy. The investigators randomized 9 patients with acute kidney injury and volume overloaded who underwent acute hemodialysis for 45 sessions in Vajira hospital between October 2017 and February 2018. In physician adjust-group (control) estimate by physical examination and fluid balance record. Primary outcome was intradialytic hypotensive episode and secondary outcome was hemodialysis-related adverse events and other clinical outcome.

NCT ID: NCT03904394 Completed - Blood Pressure Clinical Trials

Oral Nitrite Synthesis and Post-exercise Hypotension

Start date: May 9, 2017
Phase: N/A
Study type: Interventional

Exercise is probably the most effective approach to reduce blood pressure. In fact, a single bout of exercise induces a physiological response known as Post-Exercise Hypotension (PEH) where a prolonged decrease in resting blood pressure occurs in the minutes and hours after exercise. However, it is not fully understood how this response triggers. Recent evidence suggests that oral bacteria may play a key role in blood pressure control by enhancing nitrite, and then nitric oxide (NO) bioavailability under resting conditions in humans. However, no previous study has investigated whether this is a key mechanism involve in PEH. Thus, the main aim of this study was to investigate if the oral nitrate/nitrite pathway is a key regulator of PEH and vasodilation in healthy humans.

NCT ID: NCT03900000 Completed - Parkinson Disease Clinical Trials

Improved Orthostatic Tolerance = Better Cognitive Function in Parkinson's Disease

PaKogOH
Start date: May 2014
Phase: N/A
Study type: Interventional

Study on orthostatic Hypotension in Parkinson's disease

NCT ID: NCT03889730 Completed - Acute Kidney Injury Clinical Trials

Intraoperative Hypotension and Acute Kidney Injury After Off-pump Coronary Artery Bypass Grafting Surgery

Start date: March 3, 2019
Phase:
Study type: Observational

Acute renal injury (AKI) is a common complication after cardiac surgery and is associated with worse outcomes. Hypotension is an important risk factor for the development of AKI after noncardiac surgery. However, the association between intraoperative hypotension and AKI after cardiac surgery has not been fully investigated. The purpose of this study is to analyze the association between intraoperative hypotension and acute kidney injury after off-pump coronary artery bypass surgery.

NCT ID: NCT03882697 Completed - Prostate Cancer Clinical Trials

Ability of Cardio Q for Prediction of Hypotension

Start date: January 1, 2019
Phase:
Study type: Observational

Evaluation the ability of each indicator of Cardio Q in predicting hypotension after position changes in robot-assisted laparoscopic radical prostatectomy

NCT ID: NCT03882658 Completed - Acute Kidney Injury Clinical Trials

Preoperative Serum Albumin and Duration of Intraoperative Hypotension on Postoperative Acute Kidney Injury

Start date: January 10, 2018
Phase:
Study type: Observational

Acute kidney injury is one of major adverse postoperative complications. research about postoperative acute kidney injury conclude that low preoperative albumin and intraoperative hypotension is associated to postoperative acute kidney injury. However, due to ethic issue and nonlinear realtionship between these factors and postoperative acute kidney injury, the exact threshold of these two risk factors were not be able to identified. The research tried to locate the exact threshold with implementation of penalized splines by generalized additive model.

NCT ID: NCT03864692 Completed - Hypotension Clinical Trials

Prediction of Hypotension Using Perfusion Index and Pleth Variability Index After Spinal Anesthesia for C/S

Start date: January 22, 2019
Phase:
Study type: Observational

Spinal anesthesia for caesarean section is associated with a decrease in systemic vascular resistance and cardiac output and may cause hypotension in a significant portion of the parturients. Hypotension during delivery may cause maternal and fetal complications. If parturients who are likely to develop hypotension after spinal anesthesia can be identified before surgery, anesthesiologists would have opportunity to take measures such as prophylactic vasopressor administration. Perfusion index (PI) measured by pulse oximetry reflects vasomotor tone which affects the degree of hypotension after spinal anesthesia. This is a non-invasive method of assessing the relative vascular tone with the use of pulse oximeter which calculates the ratio of pulsatile versus the non-pulsatile component of the blood flow. A lower PI indicates greater peripheral vasomotor tone. Pleth variability index (PVI) is calculated using maximum and minimum values of perfusion index during respiratory cycles. PVI is one of the dynamic indices that can predict fluid responsiveness. The aim of this study is to investigate whether the PI and PVI values at different patient positions can predict hypotension during caesarean section.

NCT ID: NCT03856151 Completed - Clinical trials for Hemodialysis-Induced Symptom

To Evaluate the Effects of Heating Device (Electronic Moxibustion) in Patients With Intradialytic Hypotension

Start date: April 17, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effects of heating device among otherwise stable patients with intradialytic hypotension