Clinical Trials Logo

Hypotension clinical trials

View clinical trials related to Hypotension.

Filter by:

NCT ID: NCT03842046 Completed - Clinical trials for Cesarean Section Complications

Prevention of Hypotension During Cesarean Section

NOR-PHEN
Start date: February 16, 2019
Phase: N/A
Study type: Interventional

The aim of this double-blind randomized study will be to compare a fixed-rate prophylactic noradrenaline infusion to a fixed-rate prophylactic phenylephrine infusion during elective cesarean section under combined spinal-epidural anesthesia

NCT ID: NCT03837535 Completed - Myocardial Injury Clinical Trials

Myocardial Infarction in the Perioperative Setting

MIPS
Start date: January 1, 2019
Phase:
Study type: Observational [Patient Registry]

Acute myocardial infarction (AMI) is a significant complication following non-cardiac surgery. The investigators sought to evaluate incidence of perioperative AMI, its preoperative and intraoperative risk factors and the outcomes after this complication.

NCT ID: NCT03834454 Completed - Clinical trials for Postoperative Complications

Bupivacaine 5 mg vs 7.5 mg for Spinal Anesthesia in Cesarean Delivery in Indonesian Population

Start date: October 1, 2013
Phase: N/A
Study type: Interventional

This study aims to evaluate the efficacy of hyperbaric 5 mg bupivacaine + fentanyl 25 mcg versus hyperbaric 7.5 mg bupivacaine + fentanyl 25 mcg to lower incidence of hypotension

NCT ID: NCT03834259 Completed - Hypotension Clinical Trials

The Effects of Keeping the Patient in a Sitting Position for One Minute After Spinal Anesthesia

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

The aim of this study was to examine the effect of keeping the patient in a sitting position for 1 minute after spinal anaesthesia in elective caesarean operations, primarily on the formation of hypotension and secondarily on nausea-vomiting, the need for ephedrine and the block characteristics.

NCT ID: NCT03809065 Completed - Tissue Perfusion Clinical Trials

Effects of Nitroglycerin Versus Labetalol on Tissue Perfusion During Deliberate Hypotension

Start date: January 19, 2019
Phase: Phase 4
Study type: Interventional

Deliberate hypotension is used to provide bloodless field during endoscopic sinus surgery; however, hypotension might impair perfusion of vital organs. The aim of this work is to compare the impact of nitroglycerin and labetalol on peripheral perfusion when used for induction of deliberate hypotension

NCT ID: NCT03792906 Completed - Clinical trials for Cesarean Section Complications

Comparison of Two Norepinephrine Bolus Doses for Management of Post-spinal Hypotension During Cesarean Delivery

Start date: January 18, 2019
Phase: Phase 4
Study type: Interventional

In this study the investigators will compare two doses of norepinephrine bolus (6 mcg and 10 mcg) in management of maternal hypotensive episode after subarachnoid block during Cesarean delivery.

NCT ID: NCT03787732 Completed - Clinical trials for Acute Respiratory Failure

Preventing Cardiovascular Collapse With Administration of Fluid Resuscitation During Induction and Intubation

PREPARE II
Start date: February 1, 2019
Phase: Phase 4
Study type: Interventional

Complications are common during tracheal intubation of critically ill patients. Nearly one in five patients undergoing intubation in the intensive care unit experiences cardiovascular collapse, defined as severe hypotension, vasopressor administration, cardiac arrest or death. Cardiovascular collapse during intubation is associated with increased resource utilization and decreased survival. Administration of 500 mL of intravenous crystalloid solution beginning prior to induction may prevent cardiovascular collapse. The only prior trial examining fluid bolus administration during intubation found no effect on cardiovascular collapse or clinical outcomes overall, but a hypothesis-generating subgroup analysis suggested potential benefit to fluid bolus administration among patients receiving positive pressure ventilation between induction and laryngoscopy. Therefore, we propose a randomized trial comparing fluid bolus administration versus none with regard to cardiovascular collapse among critically adults undergoing intubation with positive pressure ventilation between induction and laryngoscopy.

NCT ID: NCT03777774 Completed - Clinical trials for Surgical Site Infection

Subgaleal Drains in Decompressive Craniectomies

VADER
Start date: January 1, 2019
Phase: N/A
Study type: Interventional

This research is about the use of subgaleal drains to prevent accumulation of blood under the skin in patients undergoing surgery to remove part of the skull(craniectomy) and its associated complications. There have been early research that shows usage of subgaleal drains maybe related to increase in complication rates after craniectomy. These complications include hydrocephalus (accumulation of fluid in the brain), new hemorrhages, infection and low blood pressure. The investigators are performing this research to determine which type of subgaleal drains would produce the least complications. With this knowledge, the investigators would be able to reduce the amount of complications for future patients that undergo surgery to remove part of the skull. The purpose of this study is to determine the rate of complications in the 3 different groups of patients using the different types of drains under the skin in surgeries that involve removal of part of the skull. All participants will undergo the required surgery to remove part of the skull (craniectomy). Participants will then be randomly assigned to either one of 3 groups which are the vacuum drain group, passive drain group or no drain group.Participants in the vacuum drain group will have vacuum drains inserted during the closing stage of the surgery. Participants in the passive drain group will have passive drains inserted during the closing stage of the surgery. Participants in the no drain group will have a drain inserted during the closing stage of the procedure but the drain will remained closed. Data will then be collected and analysed to determine if the type of drains influence the rate of complications in craniectomy

NCT ID: NCT03756935 Completed - Radiography Clinical Trials

Early Detection of Intra Operative Hypotension (IOH) During the Induction of General Anaesthesia

Start date: November 1, 2014
Phase:
Study type: Observational

During general anaesthesia, intraoperative hypotension (IOH), defined as a mean arterial pressure (MAP) drop of more than 20%, is frequent with potential deleterious effects for patients. Pulse oximeter is mandatory in the operating room making photoplethysmographic (PPG) signal and parameters such as the relative dicrotic notch height (Dicpleth) or the perfusion index (PI) readily available. The purpose of this study is to investigate whether Dicpleth and PI could detect IOH during anaesthesia induction and follow their variations during vasopressor boluses.

NCT ID: NCT03755271 Completed - Hypotension Clinical Trials

Hemodynamic Monitoring in Obstetrics

Start date: March 2, 2018
Phase:
Study type: Observational

Spinal anesthesia has long been considered the first choice technique in caesarean section, but although it is a reliable and safe procedure, it is in some cases associated with undesirable effects. Maternal hypotension after sub-arachnoid anesthesia is a reduction in systolic blood pressure below 100 mmHg or a decrease of 20% compared to baseline values. According to some authors, maternal hypotension occurs up to 80% in women undergoing caesarean section after spinal anesthesia. In order to reduce the incidence of maternal hypotension, some measures can be taken: - a reduction of aorto-caval compression by manual displacement of the uterus on the left; - hemodynamic monitoring; - administration of fluids; - optimization of the dosage of the local anesthetic; - use of vasopressors. The main objective of the study is to investigate, through the use of a continuous non-invasive hemodynamic monitoring system (Clearsight® - Edwards Lifesciences), the incidence of hypotension in pregnant women at risk undergoing spinal anesthesia due to elective cesarean section.