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Hypokinesia clinical trials

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NCT ID: NCT06452927 Not yet recruiting - Clinical trials for Lower Urinary Tract Symptoms

EEP in Patients With Urodynamically Proven DU/DA

Start date: September 2024
Phase: N/A
Study type: Interventional

The aim of this project is to create und evaluate a multicentral, retro-/prospective database for patients with urodynamically proven detrusor underactivity (DU) or acontractility (DA) secondary to a non-neurogenic aetiology, who undergo endoscopic, anatomic enucleation of the prostate (EEP).

NCT ID: NCT06438419 Not yet recruiting - Parkinson Disease Clinical Trials

Parkinsonism-Related Oscillations in the Cortico-Basal Ganglia-Thalamic Network During Movement: Beyond the Frequency Range

MOVOSCILLCBGT
Start date: June 2024
Phase: N/A
Study type: Interventional

Expression of hypokinetic and hyperkinetic motor symptoms in Parkinson's disease (PD) is associated with pathological synchronous oscillations of neuronal activity (local field potential/LFP) in the cortico-subcortical network with a wide frequency range. In the present project, we propose to study cortico-subcortical oscillations and their synchronization in patients operated for PD (subthalamic deep brain stimulation (STN-DBS)) during distinct pharmacological and stimulation conditions (hypokinetic and hyperkinetic), using a simple motor task.

NCT ID: NCT06082817 Not yet recruiting - Clinical trials for Hypoactive Sexual Desire Disorder

An Open-Label Study of 50 mg Oral Testosterone Undecanoate (Kyztrex) in Menopausal Women With Low Testosterone and HSDD

Start date: December 1, 2023
Phase: Phase 2
Study type: Interventional

This is an unblinded study to be conducted at a single research center, San Diego Sexual Medicine. Eligible subjects will receive 50 mg capsules of Kyzatrax® to be taken orally daily over a 3-month period. Multiple blood samples will be taken at baseline and on days 7, 28 and 56 to assess safety and pharmacokinetics of the testosterone. After the informed consent is signed and for up to 84 days after baseline, subjects will have serial blood samples collected in addition to other routine study procedures (e.g. vital signs measured, adverse events assessed, validated outcome scales completed).

NCT ID: NCT06020963 Recruiting - Clinical trials for Detrusor Underactivity

Can Acupoint Low Intensity Shockwave Therapy Improve Bladder Voiding Efficiency

Start date: August 11, 2023
Phase: N/A
Study type: Interventional

With the increasing of the elderly population, patients with urinary dysfunction caused by inefficiency of bladder emptying becomes much often than before. However, the current treatments for this kind of bladder dysfunction are limited and unsatisfactory. Low-intensity extracorporeal shockwave therapy (LiESWT) is a very popular emerging treatment in recent years, and abundant of literatures have confirmed that this treatment is safe and effective in myofascial pain and male erectile dysfunction. Recently, many animal experiments have showed that LiESWT could improve urinary dysfunction caused by bladder dysfunction. Taiwan based studies also reported that LiESWT could improve symptoms of overactive bladder. LiESWT is a non-drug, low-invasive and high-safety treatment, which is very suitable for elderly patients. In this study investigator combine the LiESWT and acupuncture to treat the patients with underactive bladder. Investigator hypothesize that LiESWT could improve bladder voiding efficiency.

NCT ID: NCT05837039 Recruiting - Hypoactive Delirium Clinical Trials

A Comparison of Healthcare Provider and Caregiver Perception of Discomfort in Advanced Cancer Patients Who Have a Hypoactive Delirium

Start date: March 25, 2024
Phase:
Study type: Observational

To learn about your feelings as a caregiver about the level of discomfort of patients who have hypoactive delirium (loss of contact and response to reality) and who are at the end of life

NCT ID: NCT05637593 Not yet recruiting - Parkinson Disease Clinical Trials

Rhythmic Auditory Stimulation on Upper-limb Movements in PD Patients

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to examine effects of training involving rhythmic auditory stimulation (RAS) on upper-limb movements and functions in patients with Parkinson's disease (PD). Patients will be randomly divided into two groups: the RAS group and the no-RAS group. Patients will receive training with or without the aid of RAS based on their groups. The training task is to use the right hand to take beads from one bowl to another bowl. The box and block test and the Jebsen hand function test will be used before and after training (i.e., pretest and posttest respectively) to assess patients' upper-limb speed and function. Researchers will compare scores of the box and block test and the Jebsen hand function test between the two groups at pretest and posttest to determine effects of RAS.

NCT ID: NCT05582005 Not yet recruiting - Pain Clinical Trials

An Observational Study of Emergence and Hypoactive Delirium After Anesthesia

Start date: December 2022
Phase:
Study type: Observational

Early postoperative negative behaviour (ePONB), such as pain, emergence delirium (ED) and hypoactive delirium, is a relevant clinical problem during recovery from anesthesia. Specifically, many children often present with different forms of negative behavior namely ED, hypoactive delirium or pain. Such negative behavior differs in terms of evolution, treatment, prognosis and clinical implications. Furthermore, there is overlap between tools used to measurement postoperative pain and ED. As a result, the assessment of the different forms of negative behavior are often compromised by the presence of postoperative pain. Therefore, the application of scales used to measure negative behaviour in postanesthetic, non-surgical patients aged 3 years and under scheduled for elective MRI may clarify the presence of ED, hypoactive delirium and pain. An improved understating of postanesthetic negative behavior is important in order to help implement appropriate measures so as to better treat these patients.

NCT ID: NCT05472402 Active, not recruiting - Physical Inactivity Clinical Trials

Feasibility and Acceptability of an Online Program to Promote Physical Activity Among Black Women

LADIES Online
Start date: May 22, 2022
Phase: N/A
Study type: Interventional

This study will identify strategies for modifying a physical activity intervention, previously delivered in a face-to-face format, for online implementation.

NCT ID: NCT05470751 Completed - Multiple Sclerosis Clinical Trials

GentleCathâ„¢ for Men Intermittent Catheter With FeelCleanâ„¢ Technology

Start date: February 2, 2023
Phase:
Study type: Observational

Male self catherterisng observational study.

NCT ID: NCT05359484 Completed - Clinical trials for Detrusor Underactivity

Delta Q Value to Discriminate Detrusor Underactivity From Bladder Outlet Obstruction

Start date: January 1, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

To determine the significance of delta Q value (Qmax - Qave) in discrimination between BOO and DU, to avoid invasive studies (pressure flow studies (PFSs)) and replace them with noninvasive study (uroflowmetry).