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Air Pollution and Cardiovascular Disease in Qatar: an Interventional Study to Reduce Blood Pressure — APCIQ-BP  

Metabolic Syndrome Clinical Trial

Official title:
Air Pollution and Cardiovascular Disease in Qatar: an Interventional Study to Reduce Blood Pressure: the APCIQ-BP Trial

Clinical Trial Summary

The main objective is to determine if in-home portable air cleaners provide persistent reductions in PM2.5 exposures and improvements in systolic blood pressure and biochemical parameters over 4-weeks in patients with metabolic syndrome residing in Qatar.

Clinical Trial Description

Chronic cardio-metabolic diseases such as hypertension and diabetes contribute disproportionately to global morbidity and mortality and are increasing believed to have multiple environmental influences. PM2.5 is the fifth leading risk factor for global mortality - largely due to cardiovascular disease (CVD). Reducing personal exposure to air pollution has shown promise in improving key cardiovascular risk factors (blood pressure and insulin resistance) in limited studies, but durability of these effects is not known. Personal air cleaners have been shown to decrease personal exposure to PM2.5 and reduce blood pressure in small studies and may serve as a pragmatic intervention in high-risk patients in whom air pollution is a strong contributor to cardiovascular health. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05903950
Study type Interventional
Source Weill Cornell Medical College in Qatar
Contact Charbel Abi Khalil, MD
Phone +974 4492 8484
Email cha2022@qatar-med.cornell.edu
Status Recruiting
Phase N/A
Start date June 2024
Completion date December 2025
View Details
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