Comparison of Aerobic, Resistance, and Combined Training in Overweight/Obese Hypertensive Adults

Hypertension Clinical Trial

Official title:

Compare the Effects of Aerobic, Resistance, and Combined Training in Overweight/Obese Hypertensive Adults

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05061173
• Other study ID #: REC/01083 Sidra Asghar
• Status: Completed
• Phase: N/A
• Start date: September 10, 2021
• Est. completion date: August 30, 2022

Study information

• Verified date: October 2022
• Source: Riphah International University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

To compare the effects of aerobic, resistance and combined training in hypertensive obese patients

Recruitment information / eligibility

• Status: Completed
• Enrollment: 63
• Est. completion date: August 30, 2022
• Est. primary completion date: August 30, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 40 Years to 70 Years

Eligibility

Inclusion Criteria:

• Hypertensive with BP greater than 140/90 mmHg

• Overweight and obese adults with BMI (25-40)

• Physically inactive from past 6 months assessed with pedometer. Those with step count of less than 7000 will be included

• To be able to exercise (6MWT),t hose who completed the test without any symptom

Exclusion Criteria:

• Any active systemic illness that restricts exercise

• People doing exercise on regular basis

• Any cardiopulmonary , metabolic and neurological illness

Related Conditions & MeSH terms

• Hypertension
• Obese
• Overweight

Intervention

Other:
• Aerobic exercise training Group
Aerobic Exercise includes Treadmill walking At Week 1-2, intensity of 40-45% Heart rate maximum (HR max), 3 days/week, for 30 minutes At Week 3-4, intensity of 45-50% HR max, 3 days /week, for 30 minutes At Week 5-6, intensity of 50-60% HR max 3 days per week, for 30 minutes
• Resistance Exercise Training Group
Resistive Exercises includes (a) Leg press b) Quadriceps extension c) Bicep curl d) Hip abduction. At Week 1-2, 10 repetitions 1 set, 3 days/week, for 30 minutes At Week 3-4, 2 sets of 10 repetitions, 3 times /week for 30 minutes At week 5-6, 2 sets of 10 repetitions with 5 sec hold 3 times per week for 30 minutes
• Combined Exercise Training Group
Combined Exercise training includes [Aerobic: Treadmill walking + Resistive Training: a) Leg press b) Quadriceps extension c) Bicep curl d) Hip abduction] Time will be reduced to 15 minutes for both trainings in respective weeks. Aerobic Exercise includes Treadmill walking At Week 1-2, intensity of 40-45% Heart rate maximum (HR max), 3 days/week, for 15 minutes At Week 3-4, intensity of 45-50% HR max, 3 days /week, for 15 minutes At Week 5-6, intensity of 50-60% HR max 3 days per week, for 15 minutes Resistive Exercises At Week 1-2, 10 repetitions 1 set, 3 days/week, for 15 minutes At Week 3-4, 2 sets of 10 repetitions, 3 times /week for 15 minutes At week 5-6, 2 sets of 10 repetitions with 5 sec hold 3 times per week for 15 minutes

Locations

Country	Name	City	State
Pakistan	District Headquarter Hospital - kotli	Kotli	Azad Jamu Kashmir

Sponsors (1)

Lead Sponsor	Collaborator
Riphah International University

Country where clinical trial is conducted

Pakistan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Systolic and diastolic blood pressure	Changes from the Baseline, Blood pressure is measured through sphygmomanometer	6 weeks
Primary	Body Mass Index (BMI)	Changes from the Baseline, Body mass index (BMI) will be calculated as weight (kg)/height (m2). Below 18.5 Underweight 18.5 - 24.9 Healthy Weight 25.0 - 29.9 Overweight 30.0 and Above Obesity	6 Week
Primary	Change in blood lipid profile	Change in plasma total cholesterol, high density lipoproteins cholesterol (HDL), and low density lipoproteins cholesterol (LDL) after each treatment.	6 Week
Primary	Step Count	Pedometer is a valid self-report measure of physical activity. Pedometer is used to count the average daily steps. Change from the baseline to 6 week will be compared.	6 week
Primary	Waist circumference	Waist circumference will be measured for abdominal or central fat mass. It is measured in cm at the middle distance between the last floating rib and the iliac crest using a retractable ergonomic measuring tape. Change from the baseline to 6 week will be compared.	6 week