Hypertension Clinical Trial
Official title:
Outcome After Pediatric Renal Transplantation: Cardiorespiratory Fitness, Cardiovascular Risk Factors and Quality of Life
Renal transplantation of children started in Norway in 1970.Since the beginning, >80% of
renal transplants are provided from Living Donors(mainly parents), short pre-transplant
dialysis time( median 4 months) and 50% of transplantations are performed before dialysis is
needed.This gives good premises for graft survival and avoidance of detrimental effects of
dialysis. However, renal transplanted children are subjected to an increased cardiovascular
morbidity and mortality in adulthood due to consequences of chronic renal failure and
immunosuppressive treatment.Cardiovascular death comprises 30-40% of death causes. In this
cross-sectional study we evaluate cardiovascular risk factors in childhood- and also in
young adults renal transplanted in childhood.
Focus is cardiorespiratory fitness using treadmill testing,24h BP measurements,
anthropometrics including waist circumference,echocardiography,intima media thickness of
carotids, glucose intolerance test.Participants are also requested to fill out physical
activity recalls and Quality of life questionnaires.
n/a
Observational Model: Cohort, Time Perspective: Cross-Sectional
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