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NCT00388869 Clinical Trial

Renal Artery Calcium and Hypertension

Hypertension Clinical Trial

Official title:
Calcifications of the Renal Arteries and Renal Artery Stenosis in Patients With and Without Hypertension?

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT00388869
Other study ID # HILLER-HMO-CTIL
Secondary ID
Status Not yet recruiting
Phase N/A
First received October 15, 2006
Last updated October 16, 2006
Start date November 2006

Study information
Verified date October 2006
Source Hadassah Medical Organization
Contact Nurith Hiller, MD
Phone 972-50-7874980
Email hiller@netvision.net.il
Is FDA regulated No
Health authority Israel: Israeli Health Ministry Pharmaceutical Administration
Study type Observational

Clinical Trial Summary

CT of the abdomen is a very common examination performed for various indications.One of the common findings is vascular calcifications including calcifications of the renal arteries.Calcifications in the carotid arteries and coronary arteries are good predictor for obstructive atherosclerotic disease.Stenosis of the renal arteries can cause symptomatic or asymptomatic hypertension with subsequent clinical sequelae. Therefore early diagnosis of this condition is imperative.

The goal of our study is to investigate the correlation between incidental calcifications of the renal arteries in CT examinations and the presence of actual stenosis of these vessels in patients with and without hypertension.

Description:

Every patient aged 30-100 referred for abdominal CT examination with IV contrast injection will be included in this study (total 300 patients.Prior to the examination relevant clinical data including history of hypertension and predisposing conditions for atherosclerotic disease, will be investigated. The patient will undergo conventional CT with no special procedures. The images will be review by the radiologist for the presence of renal arteries calcifications, renal arteries stenosis,plaque location, plaque burden and characterization and secondary renal pathology.

This study will not change the examination technique and is not associated with any inconvenience to the patients.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 300
Est. completion date
Est. primary completion date
Accepts healthy volunteers No
Gender Both
Age group 30 Years and older
Eligibility Inclusion Criteria:

- Every patient referred fo abdominal CT aged 30-100

Exclusion Criteria:

- Contraindication for IV contrast injection failure to demonstrate renal arteries with contrast refusal to sign an informed consent

Study Design

Observational Model: Defined Population, Primary Purpose: Screening, Time Perspective: Longitudinal

Related Conditions & MeSH terms

Locations
Country Name City State
Israel Hadassah Medical Organization Jerusalem

Sponsors (1)
Lead Sponsor Collaborator
Hadassah Medical Organization

Country where clinical trial is conducted

Israel, 

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