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Hypertension clinical trials

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NCT ID: NCT05191160 Active, not recruiting - Obesity Clinical Trials

The Soy Treatment Evaluation for Metabolic Health (STEM) Trial

Start date: November 2, 2021
Phase: N/A
Study type: Interventional

Strategies to reduce sugar-sweetened beverages (SSB) have become one of the leading public health targets to address the epidemics of obesity and diabetes. National food, nutrition, and health policies and programs have positioned low-fat milk as the preferred caloric replacement strategy for SSBs. This strategy derives from evidence that replacement of SSBs with low-fat milk is associated with reductions in weight and incident diabetes in prospective cohort studies and reduces liver fat (an important early metabolic lesion linking obesity to diabetes), as well as triglycerides and blood pressure in randomized trials. Whether these benefits hold for soy milk alternatives is unclear. There is an urgent need for studies to clarify the benefits of soy milk as an alternative to cow's milk. Our overarching aim is to produce high-quality clinical evidence that informs the use of soy as a "public health intervention" for addressing the dual epidemics of obesity and diabetes and overall metabolic health. To achieve this aim, we propose to conduct the Soy Treatment Evaluation for Metabolic health (STEM) trial, a large, pragmatic, randomized controlled trial to assess the effect of using 2% soy milk (soy protein vehicle) versus 2% cow's milk (casein and whey vehicle matched for protein and volume) as a "public health intervention" to replace SSBs on liver fat and key cardiometabolic mediators/indicators in an at risk population.

NCT ID: NCT05174078 Active, not recruiting - Obesity Clinical Trials

Food as Medicine: A Quasi-Randomized Control Trial of Healthy Foods for Chronic Disease Management

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effect of providing healthy foods and nutrition education on participants' body weight, blood pressure, and average blood sugar level. The healthy food offerings tested in this study will help determine which option is best to improve health outcomes among Cleveland Clinic Akron General patients with chronic conditions. Findings from this study could guide doctors in deciding on appropriate nutrition and dietitian services for Cleveland Clinic patients.

NCT ID: NCT05166954 Active, not recruiting - Hypertension Clinical Trials

Effect of Bariatric Surgery on Cardiac Function in Patients With Hypertension

Start date: August 1, 2018
Phase:
Study type: Observational

The purpose of this study is to investigate the effect of bariatric surgery on cardiac function assessed by echocardiography in patients with hypertension.

NCT ID: NCT05160012 Active, not recruiting - Hypertension Clinical Trials

Peer Comparison Feedback to Providers to Improve Hypertension Control

Start date: April 5, 2022
Phase: N/A
Study type: Interventional

As part of a roll out of new payment model for physicians based on hypertension control, the investigators will evaluate a monthly peer comparison message to Primary Care Providers at Penn Medicine Lancaster to see whether provider engagement with patients' overall hypertension management increases, as measured by new or increasing doses of anti-hypertensive medications.

NCT ID: NCT05156580 Active, not recruiting - Obesity Clinical Trials

Tongzhou Cohort Study

Start date: July 1, 2016
Phase:
Study type: Observational

The present study aimed to investigate the impact of obesity on long-term cardiovascular risk in elderly patients with hypertension.

NCT ID: NCT05144737 Active, not recruiting - Obesity Clinical Trials

A Virtual Cardiometabolic Health Program for African Immigrants: The Afro-DPP Program

Start date: November 21, 2021
Phase: N/A
Study type: Interventional

A pilot study titled "A Virtual Cardiometabolic Health Program for African Immigrants (The Afro-DPP Program) will be conducted to address the cardiometabolic of community-dwelling African immigrants who have multiple cardiometabolic risk factors including hypertension, Type 2 Diabetes, high cholesterol, and overweight/obesity. The proposed study will recruit a total of 60 participants and will use a non-equivalent control group design to test the effectiveness of the intervention at two African churches in the Baltimore, Washington, D.C. area. The two churches will be randomly assigned to the intervention or delayed intervention group. At the end of a 6-month follow-up period, the control church will receive the intervention (delayed control group). All participants will receive a Bluetooth-enabled digital scale (Omron Model: BCM-500) that measures body composition including Body Weight, Body Fat percentage, Visceral Fat, Skeletal Muscle percentage, Resting Metabolism and Body Mass Index. A Bluetooth-enabled blood pressure monitor (Omron Model: BP7250) will also be distributed to all participants. All participants will download the Omron Connect app which will allow the participants to sync participants' blood pressure readings and body composition readings into the app. The research team will access these readings to monitor study outcomes and participants progress during the follow-up period.

NCT ID: NCT05126082 Active, not recruiting - Hypertension Clinical Trials

PedsBP Clinical Decision Support Tool

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

The goal of the PedsBP CDS research project is to adapt a previously tested web-based clinical decision support tool that appropriately identifies high blood pressure in youth for use in a primarily rural health system and compare approaches to CDS implementation in 45 primary care clinics treating children in 3 upper Midwest states. This project will advance implementation science and address a critical need for youth at risk for cardiovascular disease and with limited access to pediatric subspecialty care.

NCT ID: NCT05125237 Active, not recruiting - Hypertension Clinical Trials

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Amiloride vs Triamterene

Start date: October 1, 2021
Phase:
Study type: Observational

This study aims to evaluate the comparative risk of dementia/Alzheimer's disease onset between patients treated with medications that target specific metabolic pathways and patients treated with alternative medications for the same indication.

NCT ID: NCT05125224 Active, not recruiting - Hypertension Clinical Trials

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Dihydropyridine Calcium Channel Blockers Versus Hydrochlorothiazide

Start date: October 1, 2021
Phase:
Study type: Observational

This study aims to evaluate the comparative risk of dementia/Alzheimer's disease onset between patients treated with medications that target specific metabolic pathways and patients treated with alternative medications for the same indication.

NCT ID: NCT05120544 Active, not recruiting - Hypertension Clinical Trials

Expanding Technology-Enabled Nurse Delivered Chronic Disease Care

EXTEND
Start date: April 21, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate whether the self-management of diabetes and hypertension can be improved with the use of mobile monitoring devices and nursing support.