MK-8527 Single-Dose Trial in HIV-1 Infected Participants (MK-8527-004)

Status Completed

Clinical Trial Summary

This is a single-dose clinical study to evaluate the safety, tolerability, pharmacokinetics, and anti-retroviral activity of MK-8527 in antiretroviral therapy (ART)-naïve participants with human immunodeficiency virus type 1 (HIV-1) infection. The primary hypothesis is that, at a dose that is safe and generally well tolerated, MK-8527 will have antiretroviral activity as measured by a reduction from baseline in plasma HIV-1 ribonucleic acid (RNA) of ≥1.0 log10 copies/mL.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Acquired Immunodeficiency Syndrome
HIV Infections
Human Immunodeficiency Virus

Clinical Trial Details

NCT number	NCT05494736
Study type	Interventional
Source	Merck Sharp & Dohme LLC
Contact
Status	Completed
Phase	Phase 1
Start date	November 17, 2022
Completion date	January 31, 2024

View Details

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