HIV Infections Clinical Trial
Official title:
On-Site Addiction Treatment With Buprenorphine in HIV Clinical Care Settings
The purpose of this study is to examine the efficacy of providing two levels of psychosocial support along with buprenorphine/naloxone (BUP) maintenance to opioid dependent patients receiving their care in an HIV clinical care setting.
The purpose of this study is to examine the efficacy of providing two levels of psychosocial
support along with buprenorphine/naloxone (BUP) maintenance to opioid dependent patients
receiving their care in an HIV clinical care setting. The proposed study will compare
Physician Management (PM), a manual-guided brief intervention that approximates the usual
counseling provided by primary care practitioners to patients with chronic medical conditions
vs. an enhanced strategy of PM with the addition of a combined drug counseling and adherence
management strategy (PM+DC/AM). DC is designed to educate the patient about the recovery
process and provide additional advice about lifestyle changes including HIV transmission risk
reduction and 12-step participation. Adherence Management (AM) is a counseling strategy
focusing on HIV medication adherence, adapted from Sorensen et al1. This research will build
on pilot work that is being completed in order to further develop and refine these counseling
interventions, determine what other psychosocial interventions might be required, and to
evaluate this model of integrated care in terms of its effects on opioid agonist therapy
retention, decreasing illicit drug use, and increasing adherence to highly active
antiretroviral therapy (HAART). Finally, it will provide data that will aid in the
formulation of guidelines and the creation of practical manuals for optimizing the provision
of this novel therapy to individuals with HIV disease and opioid dependence, as well as
provide data for future funded randomized clinical trials.
From September 2005 (start date) to December 1, 2007, the study was conducted as part of a
multi-site project that was overseen by the New York Academy of Medicine (NYAM), which is in
charge of data analysis. Following December 1, 2007, the study will continue as a local,
single-site project without further collaboration from NYAM.
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