HIV Infections Clinical Trial
— HBVOfficial title:
HBV Prevention for Homeless at Risk for HBV/HCV/HIV
Verified date | January 2017 |
Source | University of California, Los Angeles |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
In this study, researchers from UCLA and Friends Community Center will work together in designing a program to assist young homeless stimulant-using gay and bisexual homeless men to complete the hepatitis vaccine and in reducing drug and sexual activity. Using nurse case management strategies, found successful with homeless adults as well as contingency management strategies, found successful with gay and bisexual homeless adults by the community partners, the investigators will evaluate the effectiveness of a program that combines both strategies. As stimulant use threatens to increase homeless persons' risk of exposure to hepatitis A and B viruses, particularly among young users who may not yet be HBV-infected, this research is targeted to engage this group in treatment, until they are suitably protected from HBV, and hopefully reduce risk for HCV and HIV as well.
Status | Completed |
Enrollment | 451 |
Est. completion date | February 2015 |
Est. primary completion date | January 2014 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Male |
Age group | 18 Years to 39 Years |
Eligibility |
Inclusion Criteria: 1. homeless males self-reporting gay or bisexual behaviors in the last 12 months 2. age 18-39 3. methamphetamine and/or cocaine/crack use currently or in the last three months 4. no self-reported participation in drug treatment in the last 30 days 5. willing to provide informed consent 6. willing to undergo hepatitis B and C and HIV antibody testing at baseline 7. found to be HBV antibody negative Exclusion Criteria: 1. persons with Guillian Barre, or allergy to yeast or neomycin 2. monolingual speakers of languages other than English or Spanish 3. persons judged to be cognitively impaired by the nurse |
Country | Name | City | State |
---|---|---|---|
United States | Friends Community Center | Los Angeles | California |
Lead Sponsor | Collaborator |
---|---|
University of California, Los Angeles |
United States,
Nyamathi A, Shoptaw S, Cohen A, Greengold B, Nyamathi K, Marfisee M, de Castro V, Khalilifard F, George D, Leake B. Effect of motivational interviewing on reduction of alcohol use. Drug Alcohol Depend. 2010 Feb 1;107(1):23-30. doi: 10.1016/j.drugalcdep.2009.08.021. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Compare the NCMIT and SCMT programs among homeless young gay and bisexual stimulant using men with respect to completion of a HBV vaccination series administered in three doses over a four-month period. | 5 years | ||
Secondary | Document the occurrences of HCV and HIV infections as baseline among these homeless HBV antibody negative stimulant users, and the factors associated with these infections at baseline. | 5 years |
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