HIV Infections Clinical Trial
Official title:
Multicentre, Open Label, Prospective, Randomised Clinical Trial of an Antiretroviral Simplification Treatment With Efavirenz + Abacavir + 3TC Once Daily
To evaluate the proportion of patients with virological failure after 48 weeks of treatment with the combination of efavirenz 600 mg + lamivudine (3TC) 300 mg + abacavir 600 mg once daily as an antiretroviral simplification regimen.
Treatment simplification is a therapeutic strategy that allows patients with controlled
viral replication to switch to an easier-to-take antiretroviral system to promote long-term
adherence and thus maintain controlled viral load for longer, delaying the evolution of the
HIV infection.
The combination of ABC+3TC+EFV is a potent and easy-to-take regimen (2 tablets once a day)
that could be suitable for the simplification of antiretroviral treatment in patients with
controlled viral load with a regimen that includes 2 NRTI taken twice daily.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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