ALCAR Prophylaxis Study

Status Active, not recruiting

Clinical Trial Summary

The purpose of this study is to determine whether Acetyl L-carnitine can prevent the development of nerve damage, known as neuropathy, in individuals taking anti-HIV drugs over a 48-week period. In addition the safety and tolerability of Acetyl L-carnitine will be assessed.

This study compares the use of Acetyl L-carnitine or placebo (a dummy drug) in the prevention of nerve damage. The current standard of care is to use painkillers to manage the pain, with little or no effect. The possible beneficial effects of taking Acetyl L-carnitine is to prevent nerve damage as a result of anti-HIV medication.

The main purposes of the trial are:

- to look at the differences in between those on Acetyl L-carnitine versus those on placebo

- to look at the effect on state of your nervous system in the two treatment groups by measuring nerve activity

- to learn more about the safety and tolerance of Acetyl L-carnitine

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00225160
Study type	Interventional
Source	Royal Free Hampstead NHS Trust
Contact
Status	Active, not recruiting
Phase	Phase 2
Start date	November 2003

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