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A Study to Explore the Association Between Blood Pressure, HIV and Antiretroviral Therapy

HIV Infections Clinical Trial

Official title:
A Study to Explore the Association Between Blood Pressure, HIV and Antiretroviral Therapy

Clinical Trial Summary

The purpose of this study is to explore the association between blood pressure, HIV and/or its treatment in a cross sectional observational study.

Clinical Trial Description

Deaths from AIDS have declined dramatically since the introduction of highly active antiretroviral therapy in HIV infected patients. However the incidence of heart disease has increased four-fold and is now one of the major causes of death in HIV infected patients. While HIV drugs are known to adversely affect serum lipids, the evidence concerning the association between raised blood pressure (a major risk for cardiovascular disease) HIV and/or its treatment is limited and conflicting. The researchers believe it of interest to study heart disease risk factors in patients with HIV infection to avoid one premature cause of death (AIDS) being replaced with another potentially preventable cause of death and disability (heart disease). In this cross sectional observational study the researchers will systematically measure blood pressure and other cardiovascular risk factors in HIV positive patients on and off antiretroviral therapy. These individuals will be matched for age, sex and ethnic group with HIV negative individuals. ;

Study Design

Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00131807
Study type Observational
Source Imperial College London
Contact
Status Completed
Phase N/A
Start date September 2005
Completion date September 2006
View Details
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