HIV Infections Clinical Trial
Official title:
An Open Label, Randomized, Comparative Study of Zerit (d4T) + Videx (ddI) + Crixivan Versus Retrovir (AZT) + Epivir (3TC) + Crixivan in HIV-Infected, Antiretroviral Naive Subjects With CD4 Cell Counts of 200 - 700/mm3 and HIV RNA Baseline Copy Number of >= 10,000 Copies/ml
The purpose of this study is to compare the safety and effectiveness of two anti-HIV drug combinations when given to HIV-infected patients who have never been treated with anti-HIV drugs. One drug combination is stavudine (d4T) plus didanosine (ddI) plus Crixivan. The other combination is Retrovir (AZT) plus Epivir (3TC) plus Crixivan.
100 patients will be randomized to receive Zerit (Stavudine) + Videx (Didanosine) + Crixivan
(Indinavir) and 100 patients will be randomized to receive Retrovir (Zidovudine) + Epivir
(Lamivudine) + Crixivan (Indinavir).
Patients will be treated for 48 weeks.
;
Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Primary Purpose: Treatment
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