A Comparison Between Child-Pugh and Albumin-Bilirubin Scores

Hepatocellular Carcinoma Clinical Trial

Official title:

A Comparison Between Child-Pugh and Albumin-Bilirubin Scores in Patients With Spontaneous Rupture of Hepatocellular Carcinoma: A Retrospective Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03534843
• Other study ID #: Chenxp011
• Status: Completed
• Start date: January 1, 2005
• Est. completion date: January 1, 2018

Study information

• Verified date: May 2018
• Source: Huazhong University of Science and Technology
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

To compare Child-Pugh and Albumin-Bilirubin scores in patients with spontaneous rupture of hepatocellular carcinoma

Description:

To compare Child-Pugh and Albumin-Bilirubin scores in patients with spontaneous rupture of hepatocellular carcinoma. And to determine which is better in predicting long-term survival and short-term survival.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 230
• Est. completion date: January 1, 2018
• Est. primary completion date: August 1, 2015
• Accepts healthy volunteers: No
• Gender: All
• Age group: 15 Years to 76 Years

Eligibility

Inclusion Criteria:

• Be diagnosed as hepatocellular carcinoma pathologically; had a tumor rupture confirmed by Intraperitoneal exploration or clinical signs and symptoms in combination with imaging examination.

Exclusion Criteria:

• Be diagnosed as not hepatocellular carcinoma pathologically;had repeated transcatheter arterial chemoembolization(TACE) or a long history (more than 1 year) of cancer treatment; loss of follow up or without complete data.

Related Conditions & MeSH terms

• Carcinoma
• Carcinoma, Hepatocellular
• Hepatic Impairment
• Hepatocellular Carcinoma
• Rupture
• Rupture Liver
• Rupture, Spontaneous

Intervention

Procedure:
• Liver resection
Liver resection was comprised of single or multiple liver resections aiming to excise all macroscopic tumors.

Other:
• Transcatheter arterial embolization
Transcatheter arterial embolization or transcatheter arterial chemoembolization can localize the bleeding point and provide interventional embolization.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Huazhong University of Science and Technology

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Overall survival of all patients	Overall survival of all patients among different Child-Pugh and albumin-bilirubin scores	5 years
Secondary	Short-term mortality of all patients	Ninety-day mortality of all patients among different Child-Pugh and albumin-bilirubin scores	Ninety days
Secondary	Short-term mortality of surgical subgroup	Ninety-day mortality of the surgical subgroup among different Child-Pugh and albumin-bilirubin scores	Ninety days
Secondary	Short-term mortality of non-surgical subgroup	Ninety-day mortality of the non-surgical subgroup among different Child-Pugh and albumin-bilirubin scores	Ninety days