Psychological Stress Clinical Trial
Official title:
Evaluation of Serum Copeptin and Psychological Stress Level Among Healthcare Providers During COVID-19 Pandemic
Psychological stress (PSS) is one of the most common problems among healthcare providers during COVID-19 pandemic. PSS influences the homeostatic equilibrium of the body, involving activation of the sympathetic nervous system and hypothalamus pituitary adrenal (HPA) axis. Copeptin; C-terminal portion of Vasopressin (AVP) precursor is stable. Nevertheless, Evidence about influence of PSS on copeptin levels is lacking. The reason we are doing this research is to determine the level of psychological stress among healthcare providers exposed to at the time of work in intensive care unit (ICU) during COVID-19 pandemic; They will be appraised every assembly for psychological stress level; before start of duty shifts (first time), one week after start (second time) and two weeks after departure from shift duties in ICU (third time) for assessment of psychological stress level and stress hormones.
A total of 70 healthcare personnel volunteers participated; 35 physicians and 35 nurses. All healthcare providers' volunteers are in good physical health, Exclusion criteria included hypertension, diabetes mellitus, obesity BMI ≥30, subjects with serum sodium ≤135 or ≥ 145 mmol /L at baseline or females receiving contraceptive pills. During the research participants will answer a questionnaire as well as three blood samples are taken. - In the first meeting, evaluation of participant general condition; determining BMI, blood pressure. Then a small amount of blood, equal to about two millimeters, will be taken from participant arm with a syringe. This blood will be tested for serum copeptin, cortisol (fasting morning sample). The investigator will ask participant few questions to evaluate the level of stress (as anxiety, insomnia, fear of infection through questionnaire) - The second meeting, one week after work in ICU, another blood sample will be taken from participant and determine level of psychological stress. - The third meeting, two weeks after leave from ICU participant blood sample will be taken from participant to determine stress hormones and determine level of psychological stress. Duration The research takes place over six months in total. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT04680611 -
Severe Asthma, MepolizumaB and Affect: SAMBA Study
|
||
Completed |
NCT05703087 -
Positive Cueing in Knee Arthroplasty.
|
N/A | |
Completed |
NCT02541240 -
Effects of an Intervention to Enhance Resilience in Physical Therapy Students
|
N/A | |
Completed |
NCT02629016 -
Stress Reduction: A Pilot Study With Adolescents
|
N/A | |
Completed |
NCT01406028 -
Does Emotional Support Decrease In Vitro Fertilization Stress?
|
N/A | |
Completed |
NCT00121160 -
Health SMART (Stress Management and Relaxation Training) to Improve Vaccine Immune Response
|
Phase 1 | |
Completed |
NCT02621775 -
Effectiveness of Two Stress Management Programs in Adaptation Disorder With Anxiety (ADA)
|
N/A | |
Recruiting |
NCT04474418 -
Psychometric Characterization of Patients With Cardiac Arrhythmias
|
||
Completed |
NCT03310112 -
Mindfulness Training in U.S. Army Cohorts
|
N/A | |
Terminated |
NCT03893617 -
Brief Stresses Experimental Study
|
Phase 1 | |
Active, not recruiting |
NCT05542498 -
Promoting Stress Management and Engagement in Introductory Physics Courses With Mindfulness and Relaxation
|
N/A | |
Completed |
NCT02394899 -
Improving Parental Psychosocial Functioning and Early Developmental Outcomes in Children With Sickle Cell Disease
|
N/A | |
Terminated |
NCT00962273 -
The Pandemic Stress Vaccine: A Resource to Enhance the Resilience of Healthcare Workers Facing an Infectious Outbreak
|
N/A | |
Completed |
NCT00451126 -
Moderating Impact of Various Emotion Personality Factors on Salivary Cortisol Response to a TSST
|
N/A | |
Completed |
NCT06051500 -
Psychological and Physiological Effects of Different Objects of Breath Meditation
|
N/A | |
Completed |
NCT02801045 -
Art Therapy in Palliative Care: Study of Identification and Understanding of the Mechanisms of Change in the Patient
|
N/A | |
Completed |
NCT03308344 -
Mindfulness Training in Military Spouses
|
N/A | |
Recruiting |
NCT06029348 -
Cerebrovascular Health and Resilience in Midlife
|
N/A | |
Completed |
NCT04484649 -
Sleeping Healthy/Living Healthy Development
|
N/A | |
Completed |
NCT05869006 -
The Effect of Designed SIA Instrument Supported Interpersonal Relations-Based Group Practice on Psychological Well-Being and Creativity
|
N/A |