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Study of Hemostasis During the Atrial Fibrillation Ablation Procedure — EHPAFAVE  

Hemostasis Clinical Trial

Official title:
Study of Hemostasis During the Atrial Fibrillation Ablation Procedure

Clinical Trial Summary

Anticoagulation monitoring is done by monitoring the ACT (Activated Clotting Time) with an objective greater than 300 s. Until now, treatment with direct oral anticoagulant (for the prevention of thromboembolic events of atrial fibrillation) was interrupted a few days before the procedure in order to limit the risk of per-procedural bleeding. However, 3 recent randomized studies concerning the 3 DOACs available suggest that treatment should not be interrupted during the entire operative period. The operation therefore takes place under double anticoagulation with a direct oral anticoagulant and unfractionated heparin. Under these conditions, ACT monitoring can no longer be considered a reliable means of measuring the level of anticoagulation. It was therefore necessary to explore the hemostasis of these patients in a broad way in order to avoid any risk of overdose of UFH (Unfractionated Heparin) during the procedure.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05128110
Study type Observational
Source University Hospital, Strasbourg, France
Contact
Status Completed
Phase
Start date January 1, 2021
Completion date December 31, 2021
View Details
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