Hemostasis Clinical Trial
Official title:
Delivering Transcutaneous Auricular Neurostimulation to Regulate Platelet Activity in Healthy Human Subjects
This study is designed as a randomized, double-blind, sham-controlled, single-center research study in which healthy adults will be randomized 1:1 into one of two experimental groups, to receive transcutaneous auricular vagus nerve stimulation (taVNS) targeting either the auricular branch of the vagus nerve (ABVN) or tAN, which targets the ABVN and the auriculotemporal nerve (ATN): 1. Group 1: Sham taVNS followed by active taVNS 2. Group 2: Sham tAN followed by active tAN Participants will receive 30 minutes of sham stimulation (taVNS or tAN), followed by active stimulation (taVNS or tAN). Blood biomarkers (local and systemic) will be measured before and at several timepoints after stimulation to measure the molecular and cellular effects of the device.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05335525 -
Post-market Clinical Investigation of the Angio-Seal™ VIP VCD (ANGIO-SEAL CLOSE)
|
||
| Completed |
NCT02583854 -
Comparison Study of Compression Devices Used in Transradial Coronary Angiography
|
N/A | |
| Completed |
NCT01388491 -
A Multinational Study to Evaluate the Effects of a 28-Day Oral Contraceptive on Hemostatic Parameters in Healthy Women
|
Phase 2 | |
| Recruiting |
NCT04728087 -
ACCEL Absorbable Hemostat
|
N/A | |
| Recruiting |
NCT05323448 -
Efficacy of ARISTA-AH for Restoring Hemostasis Following Posterior Long-segment Spinal Fusion.
|
N/A | |
| Recruiting |
NCT06078735 -
Vascular Closure With a Device Compared to Manual Compression After Atrial Fibrillation Ablation: The LockeT II Study
|
N/A | |
| Completed |
NCT03907111 -
Compare the Hemostatic Effectiveness of Chitosan Gauze With Traditional Gauze on Open Wound on 10 Participants.
|
N/A | |
| Recruiting |
NCT05875272 -
Interchangeability of Arterial Coagulation and Venous Coagulation, in the Context of Cardiac Surgeries Under Cardiopulmonary Bypass, Using the DMDiv Hemochron Signature Elite
|
||
| Completed |
NCT04593667 -
Randomized Study of Accelerated Radial Arterial Hemostasis
|
N/A | |
| Completed |
NCT01252186 -
A Multicenter Study to Evaluate the Effects of a 91-Day Extended Cycle Oral Contraceptive on Hemostatic Parameters in Healthy Women
|
Phase 2 | |
| Terminated |
NCT00802633 -
Radical Cystectomy: Can We Improve Our Surgical Technique With the Ligasure Impact Tissue-Sealing Device?
|
N/A | |
| Completed |
NCT02034799 -
Phase IV Bioseal Study in Brain Tumor Surgery
|
Phase 4 | |
| Terminated |
NCT03873168 -
Post-Market Evaluation of HEMOBLAST™ Bellows in Open Gynecological, Urological, ENT, Head, Neck, and Vascular Surgeries
|
||
| Recruiting |
NCT04377490 -
Thrombo Embolic Events in Hospitalized Patients With Covid-19 Serious Acute Pneumopathy
|
||
| Completed |
NCT00449410 -
Silent Cerebrovascular Lesion and Cognitive Decline Prevention by Cholesterol Lowering in Elderly AF Patients
|
Phase 4 | |
| Completed |
NCT03873181 -
Post-Market Evaluation of HEMOBLAST™ Bellows in Laparoscopic Abdominal, Gynecological, and Urological Surgery
|
||
| Completed |
NCT04660721 -
A Study Evaluating the Safety and Preliminary Efficacy of sFilm-FS in Controlling Parenchymal Bleeding During Elective Hepatic Surgery
|
Phase 1/Phase 2 | |
| Recruiting |
NCT05653843 -
MANTIS Endoscopic Clipping Study
|
||
| Completed |
NCT00658723 -
The Fibrin Patch Soft Tissue Study
|
Phase 2 | |
| Recruiting |
NCT03323359 -
Efficacy and Tolerability of Hemopatch After Hepatic Resection
|
N/A |