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Hemorrhoids clinical trials

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NCT ID: NCT03938714 Completed - Length of Stay Clinical Trials

Hemorrhoidectomy in Patients With Grade III and IV Disease:Harmonic Scalpel Compared With Conventional Technique

Start date: August 27, 2015
Phase: N/A
Study type: Interventional

Hemorrhoidectomy is the treatment of choice for grade 3 and 4th degree hemorrhoids. Various surgical technique has been used to improve the outcome of the procedures performed in respect to operative time ,post operative pain and hospital stay. This study compares the conventional closed technique with harmonic scalpel technique which is a device regulated with ultrasonic waves to perform the procedure with minimal postoperative complication as well as decreasing the prolong stay in hospital.

NCT ID: NCT03903536 Completed - Clinical trials for Thrombosed External Hemorrhoid

Thrombosed External Hemorrhoids: Comparison of the Thrombectomy and Local Excision Procedures in Terms of Results and Outcome (TEH)

TEH
Start date: September 1, 2020
Phase:
Study type: Observational [Patient Registry]

The primary aim of the current study is to evaluate and compare 6-month complication rates after thrombectomy and local excision treatments. The investigators aim to compare thrombectomy and local excision treatments in many different aspects: - The investigators will follow these patients for 6 months by scheduling follow-up visits (or by phone if the patient cannot attend) 4 times during this period (1st week, 1st month, 3rd month, 6th month). - The investigators will examine bleeding, pain, anal stricture/stenosis, infection, time until return to normal daily activity, relapse and incontinence after treatment - To assess quality of life outcomes, the investigators use the 36-Item Short Form Health Survey (SF-36). These measures rely upon patient self-reporting and are utilized for routine monitoring and assessment of care outcomes in patients. - The investigators will use the Wexner incontinence score for assessment of incontinence. In each hospital, medical students, residents and surgeons can be involved in the study. In the following 6-month period, all collaborators will be collecting the data of the patients who have been operated for external hemorrhoids via the thrombectomy or local excision procedures.

NCT ID: NCT03848468 Completed - Pain, Postoperative Clinical Trials

Comparison Study: Ligasure Versus Conventional Hemorrhoidectomy in III and IV Degree Hemorrhoids.

Start date: April 1, 2014
Phase: N/A
Study type: Interventional

A comparison study was performed between Ligasure and Milligan morgan hemorrhoidectomy to find out the outcome between these two techniques in 3rd and 4th degree hemorrhoids.This advance vessel sealing device is used to seal the pedicle of the vessel and does not burn the surrounding tissues , so the outcome was monitored in terms of operative time, post operative pain pain, duration of wound healing in 3 weeks and return to normal activities

NCT ID: NCT03797703 Completed - Hemorrhoids Clinical Trials

Efficacy of Lidocaine Gel Enema After Endoscopic Hemorrhoid Band Ligation for Relief of Post Procedural Pain

Start date: November 26, 2018
Phase: Phase 1
Study type: Interventional

This is a prospective study to assess the utility of Lidocaine Hydrochloride 2% gel enema (Hi-Tech Pharmacal Co., Inc.) in reducing post-procedural pain after endoscopic band ligation of internal hemorrhoids. Briefly, patients will be consented prior to entry into the study. During the endoscopic band ligation procedure, patients will be blindly placed into the treatment arm or control arm. The treatment arm will receive 15 ml enema of lidocaine gel immediately upon cessation of the procedure. In the placebo arm, oral pain medications will be provided. Researchers will assess pain following the procedure at 1 hour, 24 hours and 48 hours via telephone call. Another telephone call will be performed at 72 to 96 hours to assess any side effects of the medication.

NCT ID: NCT03791775 Completed - Clinical trials for Second-degree Hemorrhoids

Efficacy and Safety of Polidocanol Foam 3% in the Treatment of II Degree Hemorrhoidal Disease

SCLEROFOAM
Start date: January 2, 2019
Phase: Phase 2
Study type: Interventional

Hemorrhoidal disease (HD) is one of the oldest and most common proctologic diseases that has been described with an estimated prevalence between 4.4% and 86%. Despite the proposal of three mechanisms that might underlie haemorrhoidal development - the varicose vein theory, the vascular hyperplasia theory and the sliding anal-lining theory, the exact pathophysiology of symptomatic hemorrhoid disease is poorly understood. HD seems to be the most common cause for rectal bleeding, or hematochezia, and the second most frequent cause for severe rectorrhagia after diverticulitis. The blood is bright red and coats the stool at the end of defection. Other symptoms include pain, mucous discharge, itching or the sensation of tissue prolapse. The most widely accepted classification is the Goligher classification: - Grade I: hemorrhoids bleed but do not prolapse out of the anal canal; - Grade II: hemorrhoidal cushions prolapse outside of the anal canal on straining or during bowel movements, but reduce spontaneously; - Grade III: hemorrhoidal cushions prolapse outside the anal canal on straining and require manual reduction; - Grade IV: hemorrhoidal prolapse is irreducible even with manipulation

NCT ID: NCT03757078 Completed - Acute Hemorrhoids Clinical Trials

Study to Find Out How Symptoms Severity Changes During the Standard Course of Treatment With the Cream Relief Pro and Suppositories Relief Pro (Active Ingredients Are Fluocortolone + Lidocaine) in Patients Suffering From Twisted and Bulging Veins in the Rectal Area (Acute Hemorrhoids)

Start date: November 30, 2018
Phase:
Study type: Observational

In this study researcher wanted to learn more about the changes of biggest twisted and bulging veins in the rectal area (hemorrhoids) and changes of symptoms during a treatment period with the cream Relief Pro and suppositories Relief Pro. The study collected information on the treatment satisfaction of patients and their physicians with the prescribed treatment by using questionnaires. There were 3 visits at the physician's clinic for this study: one initial visit and 2 follow-up visits over a period of 2 weeks.

NCT ID: NCT03743311 Completed - Hemorrhoids Clinical Trials

Data on the Impact of Different Treatment on the Quality of Life of Patients With Acute and Chronic Hemorrhoid Disease

EQUALISER
Start date: March 1, 2019
Phase:
Study type: Observational

The program is aimed at obtaining data on the impact of the method and type of treatment on the quality of life of patients with acute or chronic hemorrhoids with option of conservative treatment with Detralex

NCT ID: NCT03545724 Completed - Hemorrhoids Clinical Trials

Effectiveness & Safety of Neofitoroid® in Hemorrhoidal Disease

Start date: February 7, 2018
Phase: N/A
Study type: Interventional

Evaluation of the effect and safety of NeoFitoroid® in reducing symptoms in patients with hemorrhoidal disease.

NCT ID: NCT03479489 Completed - Clinical trials for External Hemorrhoid Thrombosed

Use of Human Dehydrated Amnion Chorion Allograft in Closed Hemorroidectomy

Start date: February 5, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the safety and effectiveness of human dehydrated amnion chorion allograft in closed hemorrhoidectomy as assessed by patient and wound assessments.

NCT ID: NCT03405922 Completed - Hemorrhoids Clinical Trials

Perianal Nerval Block in Proctological Interventions

Start date: February 1, 2018
Phase: Phase 4
Study type: Interventional

The aim of this study is to evaluate whether a local perianal block performed during a proctological intervention can reduce the postoperative pain.