Clinical Trials Logo

Hemiplegia clinical trials

View clinical trials related to Hemiplegia.

Filter by:

NCT ID: NCT01623622 Completed - Clinical trials for Severe Upper Limb Hemiplegia

Study of HC-58 in Upper Limb Hemiplegic Patients After Stroke

Start date: July 2012
Phase: Phase 2
Study type: Interventional

The purpose of this study is to investigate the efficacy and safety of HC-58 in patients with severe upper limb hemiplegia following stroke.

NCT ID: NCT01569386 Completed - Physical Activity Clinical Trials

Low Intensity Physical Activity Leads to Improvement in Brachial-ankle Pulse Wave Velocity of Hemiplegics

LIPA
Start date: June 2004
Phase: Phase 2
Study type: Interventional

Low intensity physical activity by half squat of the elderly people with hemiplegia significantly slow down the pulse wave velocity of the arteries of the lower limbs of the paralyzed side within 8 weeks.

NCT ID: NCT01447810 Completed - Brain Tumor Clinical Trials

Constraint-Induced Movement Therapy in a Pediatric Oncology Population

SJCIT
Start date: October 2011
Phase: N/A
Study type: Interventional

Hemiplegia (weakness or poor muscle function on one side of the body) is a neurological impairment which can occur in children as a result of a brain tumor or related treatment. This impairment can negatively impact the child's functional abilities and movement development, making it difficult for them to play, learn to feed, dress or bathe themselves, and to participate fully in home, daycare, or school environments. Poor movement skills may also impact overall quality of life. Constraint Induced Therapy is a rehabilitation technique which has been found to improve the child's abilities to move their arms following neurological injuries like stroke and traumatic brain injury in both adults and children. The aim of this study is to evaluate the feasibility of implementing a constraint induced movement therapy program in a small group of children with a brain tumor and hemiplegia. Children who participate in the program may experience improved ability to use their weak arm leading to increased participation in meaningful activity and improved quality of life.

NCT ID: NCT01413594 Completed - Cerebral Palsy Clinical Trials

Bimanual Training in Children With Hemiplegia

HABIT
Start date: July 2011
Phase: N/A
Study type: Interventional

A randomized control trial of bimanual training in children with hemiplegia. The protocols have been developed at Columbia University to be child friendly and draws upon our experience since 1997 with constraint-induced movement therapy in children with cerebral palsy. The investigators will test the hypothesis that bimanual training (HABIT) will result in improved hand function in children with hemiplegia.

NCT ID: NCT01336517 Completed - Hemiplegia, Spastic Clinical Trials

Evaluation of the Effect of an Ankle Foot Orthoses for Ambulatory Function

Start date: August 2007
Phase: N/A
Study type: Observational

The main purpose of this investigation is to evaluate the effect of a lower leg brace on walking efficiency and community walking in people who have weakness in one side of the body caused after a stroke. The evaluation will consist of several tests that will evaluate movement, tightness, balance and sensation in affected leg.

NCT ID: NCT01257646 Completed - Stroke Clinical Trials

Observation of the Gait Cycle in Patients With Hemiplegia in Order to Improve the Triggering of Functional Electrical Stimulation

MASEA
Start date: May 2011
Phase: N/A
Study type: Observational

The main objective of this study is the estimation and comparison of the dephasing between the switch heel and the inertial placed on the paretic foot compared to the events of the gait cycle determined by a Gaitrite system (beginning and end of the swing phase) in conditions without stimulation.

NCT ID: NCT01232218 Completed - Stroke Clinical Trials

Treatment Protocol for Hemiplegic Shoulder Pain

TPHSP
Start date: October 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if a specific stretching and strengthening protocol, in addition to current standard treatment, is more effective for treating post-stroke shoulder pain than current standard treatment alone.

NCT ID: NCT01157494 Completed - Cerebral Palsy Clinical Trials

Validity of Manipulation Taxonomy of Spastic Hemiplegic Cerebral Palsy (CP) Forms

Start date: April 2010
Phase: N/A
Study type: Observational

In recent years Ferrari et al. proposed a new classification of manipulation in children with spastic hemiplegia which describes five different classes by analyzing and integrating the kinematic patterns of the hand and its functional use. The investigators believe that this classification provides the clinician with clinically meaningful information, by identifying the useful strategies spontaneously adopted by the children during manipulation tasks. The aim of this study is to determine the criterion validity of the new classification of the pattern of manipulation in children with spastic hemiplegia by correlating hand manipulation classes with both the scores of the Assisting Hand Assessment and the scores of the Melbourne Assessment of Unilateral Upper Limb Function.

NCT ID: NCT01116466 Completed - Stroke Clinical Trials

Clinical Study to Evaluate the Implantation of the ActiGait Drop Foot Stimulator System

Start date: August 2009
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the efficacy and safety of surgical procedure involving ActiGait - implantable drop foot stimulator.

NCT ID: NCT01104064 Completed - Stroke Clinical Trials

Pediatric Hemiplegia: Synergistic Treatment Using rTMS and CIT

Start date: February 2010
Phase: Phase 1
Study type: Interventional

The strategy in rehabilitating pediatric hemiplegia is to overcome "developmental disuse". Disruption of the excitability in the non-stroke hemisphere, with resultant increased excitability (disinhibition) in the stroke hemisphere, can be achieved with low-frequency repetitive transcranial magnetic stimulation (rTMS), a noninvasive method of stimulating targeted areas of the brain. Furthermore, the disruptive effects of low-frequency rTMS can be increased and prolonged by preceding it with 6-Hz priming stimulation. We have recently demonstrated the safety of this priming/low-frequency rTMS in adults with stroke and we are currently engaged in an NIH-funded study exploring the effectiveness, mechanism and safety of serial treatments of rTMS combined with motor learning training. Very little research, however, has been attempted on interventions to promote brain reorganization and recovery in hemiplegia in children. Thus, this study will determine the effectiveness, mechanism, and safety of 5 treatments of 6-Hz primed low-frequency rTMS applied to the non-stroke hemisphere and combined with constraint induced therapy (CIT) to promote recovery of the paretic hand. Fifteen children with pediatric hemiplegia, age 8 -16 years, at each of two pediatric medical facilities (total N = 30), will be randomly assigned to one of two treatment groups that will receive treatment for 2 weeks. The rTMSreal/CIT group will receive alternating days of the real rTMS and CIT for 5 treatments of each. The rTMSsham/CIT group will receive alternating days of sham rTMS with real CIT for 5 treatments of each. Subjects will be tested at pretest and posttest. The hypotheses are: 1) the rTMS treatment will show no serious side effects, 2) both groups will show improvement in hand function but the rTMSsham/CIT group will show significantly greater improvement, 3) the rTMSreal/CIT group will also show significantly greater improvements in brain reorganization measured by paired-pulse TMS testing, cortical silent period testing, and fMRI. The proposed research is important because very little research on rehabilitation-induced brain reorganization has been done in pediatric hemiplegia. It is innovative because it applies a technique never used before, i.e. 6-Hz primed low-frequency rTMS combined with CIT. The potential impact of this research is a radical change to pediatric rehabilitation that accomplishes a higher functional recovery.