Heart Failure With Reduced Ejection Fraction Clinical Trial
Official title:
Comparison of Treatment and Doses of Drugs in Patient With Heart Failure Reduced Ejection Fraction (HFREF) Between Asyut University Hospital and Guidelines of European Society 0f Cardiology (ESC)
Analyze the epidemiology and outcome of all patients with heart failure with reduced ejection fraction (HFrEF) presented to Asyut university hospital (AUH) and to identify factors associated with mortality and all-cause hospitalization at a duration of 6 months follow-up.
Heart failure (HF) is nowadays an important health problem and associated with high use of
resources and healthcare cost, but the prevalence of heart failure is increasing due to
better care and treatment of HF and to the aging of the population. Epidemiology of HF is
changing and shifting towards a higher prevalence of patients with HF with preserved ejection
fraction. Moreover, the outcome of HF is grim. The mortality rate is high and
hospitalizations are frequent and associated with worse outcomes. The majority of studies
that analyzed HF outcomes have focused on HF hospitalizations. However, in patients with HF,
all-cause hospitalizations can affect up to 23-58% of the patients at 1-year follow-up and
non-cardiovascular hospitalizations are associated with risk of subsequent mortality similar
to cardiovascular hospitalizations. Despite the evidence that all-cause hospitalizations are
detrimental in HF patients, few studies have analyzed whether the factors associated with
all-cause and HF-hospitalizations are different in HF patients.
However, the characteristics and outcome of HF patients are not well described in developing
countries like Egypt. Documenting patients' characteristics and the outcome might improve
management of comorbidities associated with heart failure patients in Egypt as well as the
disease outcome, However, characteristics and outcome of HF patients are not well described
in developing countries like Egypt. Documenting patients' characteristics and the outcome
might improve management of comorbidities associated with heart failure patients in Egypt as
well as the disease outcome, However, characteristics and outcome of HF patients are not well
described in developing countries like Egypt. Documenting patients' characteristics and the
outcome might improve management of comorbidities associated with heart failure patients in
Egypt as well as the disease outcome However, characteristics and outcome of HF patients are
not well described in developing countries like Egypt. Documenting patients' characteristics
and the outcome might improve the management of comorbidities associated with heart failure
patients in Egypt as well as the disease outcome
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