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Heart Diseases clinical trials

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NCT ID: NCT01507805 Recruiting - Clinical trials for Coronary Heart Disease

Electroacupuncture Preconditioning on Geriatric Noncardiac Surgery

Start date: February 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to observe whether the electroacupuncture (EA) preconditioning for five days before operation can improve the outcomes of patients with coronary heart disease undergoing geriatric non-cardiac surgery.

NCT ID: NCT01503307 Completed - Clinical trials for Congenital Heart Disease

Parenting After Infant Congenital Heart Defect Diagnosis

Start date: January 2009
Phase:
Study type: Observational

The purpose of this research study is to learn about parents' experiences following diagnosis of a fetal/neonatal Congenital Heart Defect (CHD). Nurses, physicians, and other health-care clinicians will benefit from an improved understanding of what the diagnosis means to parents and what they expect concerning the infant, being a parent, and caregiving tasks and responsibilities. The investigators expect that the knowledge gained will increase clinicians' ability to respond to parents' needs.

NCT ID: NCT01502943 Completed - Clinical trials for Coronary Heart Disease

Studies of Traditional Chinese Medicine Clinical Efficacy Evaluation Index

Start date: May 2011
Phase: Phase 4
Study type: Interventional

The purpose of the trial is to take stable angina pectoris of coronary heart disease (CHD) as examples to build a standard evaluation system for efficacy of traditional Chinese medicine (TCM). 1. Studies of evaluating reliability, validity and reactivates of Patients Report Outcomes of CHD and self-administrated scale of Stable Angina Pectoris 2. research on all indicators of CHD, and analyze their characteristics, target and function 3. theory of Invigorating Spleen to Remove Phlegm or replenish Qi, and activating blood and dissolving stasis as an example for clinical efficacy evaluation.

NCT ID: NCT01502332 Recruiting - Cardiac Disease Clinical Trials

Intensive Alveolar Recruitment Protocol After Cardiac Surgery

Start date: December 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate prospectively the impact of two protective mechanical ventilation strategies, both using low-tidal volume ventilation (6 mL/kg/ibw) after cardiac surgery. The study will select patients presenting signals of deficient gas exchange (PaO2/FIO2 < 250 at a PEEP of 5 cmH2O) in the immediate post-operative period. An aggressive alveolar recruitment protocol applying opening pressures of 45 cmH2O, followed by ventilation with PEEP = 13 cmH2O, will be compared to the standard alveolar recruitment protocol of the institution, where an opening pressure of 20 cmH2O in the airways is followed by ventilation with PEEP = 8 cmH2O. After a stabilizing period of four hours of controlled mechanical ventilation, the patients will follow the routine weaning protocol and physiotherapy protocol of the institution.

NCT ID: NCT01501110 Completed - Clinical trials for Acute Myocardial Infarction

Effects of N-acetylcysteine on Low T3 Syndrome

Start date: November 2011
Phase: Phase 4
Study type: Interventional

The propose of this study is to determine whether N-acetylcysteine is effective in reversing the changes in thyroid hormones seen in critical illness, known as the low T3 syndrome.

NCT ID: NCT01498276 Completed - Cancer Clinical Trials

Family Genetics Health Education and Healthy Behaviors

Start date: January 3, 2012
Phase:
Study type: Observational

Background: - Family-based approaches to reduce disease risk and promote healthy behaviors may be better than targeting individuals. Risk assessments based on family health history may help educate families on disease risks and encourage them to change physical activity and food choices. Specifically, researchers want to better understand the role of mothers in teaching healthy behaviors to their families. Objectives: - To determine mothers influence on diet and health-related behaviors. - To study an intervention tool that connects family health history and disease risk. Eligibility: - 18 years of age who have at least one child living at home. Design: - Participants will complete a survey over the phone. The survey will take 30 to 40 minutes to complete. The survey will collect family health history on heart disease, diabetes, colorectal cancer, and breast cancer. - Researchers will give participants a Family Health Package (FHP). The FHP will provide information on family health history and disease risk. It will also recommend behaviors that can reduce health risks. - Two weeks after sending the FHP, participants will complete a phone survey about the FHP materials and their social networks. - Some participants will be invited to focus groups. The focus groups will explore diet and health behavior. They will look at food purchasing and preparation and meal sharing. The groups will also discuss attitudes toward healthy eating and physical activity. Each focus group will last 1 to 2 hours. - Participants will be asked to complete an electronic survey regarding participants health status, causal health beliefs, risk perceptions, and intentions to communicate health information. - Then, participants will have the opportunity to use the electronic version of the FHP, which will assess family health history. - After using the FHeP, participants will complete a short electronic survey to identify knowledge and understanding gained from the use of the application, changes in communication intentions, and suggestions for improvements to the application. - Upon completion of the electronic portion of the study, a study team member will conduct a semi-structured interview to allow the participants to qualitatively evaluate their user experience, including satisfaction and usefulness. - This study process will take approximately 60-90 minutes.

NCT ID: NCT01495520 Not yet recruiting - Clinical trials for Ischemic Heart Disease

Ranolazine for Improving Symptoms of Palpitations

RYPPLE
Start date: January 2014
Phase: Phase 4
Study type: Interventional

Patients with ischemic heart disease often report multiple symptoms, including angina and palpitations. Ranolazine has antiarrhythmic effects which are largely a result of the drug's effect on multiple ion channels. It remains unknown, however, whether the favorable effects of ranolazine on symptoms and arrhythmias are maintained over time. Aim of this study is to test the hypothesis that chronic treatment with ranolazine can improve the symptomatic status of patients with ischemic heart disease by reducing the occurrence of palpitations.

NCT ID: NCT01489449 Completed - Clinical trials for Coronary Heart Disease

Bare Metal Stent Versus Drug Coated Balloon With Provisional Stenting in Non-ST-Elevation Myocardial Infarction

PEPCADNSTEMI
Start date: December 2012
Phase: Phase 4
Study type: Interventional

The aim of the present trial is to assess the efficacy of the standalone use of SeQuent(R) Please coated balloon compared to a bare metal stent (BMS) in patients with NSTEMI.

NCT ID: NCT01487941 Completed - Cardiac Disease Clinical Trials

Setrox JS Master Study

Start date: December 2011
Phase: N/A
Study type: Observational

The purpose of this study is the evaluation of safety and efficacy of the pacemaker lead "Setrox JS".

NCT ID: NCT01486836 Completed - Cardiac Disease Clinical Trials

Lumax DX / Linox DX Evaluation

Start date: November 2011
Phase: N/A
Study type: Observational

The objective of this study is to investigate the safety and efficacy of the Lumax DX / Linox DX system. No hypothesis has been defined.