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Heart Diseases clinical trials

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NCT ID: NCT02923440 Recruiting - Clinical trials for Congenital Heart Defects

Creation of a French South-Eastern Database and DNA-bank of Congenital Heart Disease to Explore the Genetic Pathways

SEA-HD
Start date: January 17, 2017
Phase: N/A
Study type: Interventional

Congenital heart defects are seen in 0,8% of life births. In France this means more than 5000 newborns per year. The south-east region of France is particularly affected as a result of a higher birth rate and consanguinity, when compared to other regions. The majority of congenital heart diseases remain unexplained. Genetic causes are indisputable but remain poorly understood. Genetic research needs the availability of a large-scale DNA collection, guided by a robust phenotypic classification. Such a DNA-bank has been created in Paris (CARREG DNA bank, created by the M3C reference centre for congenital heart diseases). Such a bank is currently unavailable in south-east France. To transport biological specimens from Marseille to Paris would be very expensive. In addition, the whole infrastructure required for correct diagnosis and classification of the congenital heart diseases, for sampling, for storage of the samples and genetic analysis, does exist in our AP-HM hospital and in our AMU research unit. For those reasons it is highly preferable to elaborate such a database and DNA-bank locally. The acronym SEA-HD (South-EAst-Heart-Diseases) would be used to name this DNA-bank

NCT ID: NCT02921464 Recruiting - Clinical trials for Stable Ischemic Heart Disease

Florida Cardiovascular Quality Network

FCQN
Start date: June 2016
Phase: N/A
Study type: Observational [Patient Registry]

Florida Cardiovascular Quality Network Application of Clinical Decision Support Software Tools at the Point of Care in Patients with Stable Ischemic Heart Disease - a Quality Outcomes Registry

NCT ID: NCT02920125 Completed - Clinical trials for Coronary Artery Disease

Study the Result of Ayurvedic SUVED & Reimmugen (Colostrum) Treatment on Vascular Disease, CAD, CVA, DVT.

SHARP
Start date: January 2016
Phase: Phase 3
Study type: Interventional

To evaluate the benefits of Ayurvedic SUVED & REIMMUGEN Colostrum for reduction/reversal of symptoms and study clinical progress in Vascular disease; CAD, CAV, Stroke, DVT patients.

NCT ID: NCT02917980 Completed - Clinical trials for Data Collecting and Analyzing of Different Treatment of Structural Heart Diseases

Surgery and Transcatheter Intervention for Structural Heart Diseases

Start date: January 2016
Phase:
Study type: Observational [Patient Registry]

This project aimed to optimize the therapeutic strategy for structural heart disease by choosing optimal treatment, such as,surgical treatment,interventional and surgery combined with interventional hybrid treatment. Thereby improve successful rate of clinical treatment, and establish the guideline for treatment of structural heart disease.At the same time,online registration database for structural heart disease will be established to further data analysis and objective assessment of clinical curative effect for structural heart disease in China.

NCT ID: NCT02917213 Completed - Stroke Clinical Trials

Imaging Silent Brain Infarct And Thrombosis in Acute Myocardial Infarction

ISBITAMI
Start date: September 2016
Phase:
Study type: Observational

This project aims to assess the ability of cardiac imaging (cardiac MRI and Doppler-echocardiography) post-processing tools to predict a combined end-point of intraventricular thrombosis, silent brain infarcts, clinical stroke and peripheral arterial embolism in patients with first acute myocardial infarction and ventricular dysfunction.

NCT ID: NCT02914392 Recruiting - Clinical trials for Congenital Heart Disease

Study on the Relationship Between Maternal Exposure to Environmental Factors and Fetal Congenital Heart Disease

Start date: May 18, 2017
Phase: N/A
Study type: Observational

The objective of this study is to research the relationship between maternal exposure to environmental factors and fetal congenital heart disease in a community-based case-control study.

NCT ID: NCT02909543 Recruiting - Clinical trials for Women With Congenital Heart Diseases

The Life Experience of Young Women (Age 18-38) Who Live With Congenital Heart Disease

Start date: September 2016
Phase: N/A
Study type: Observational

This research will focus on young women between the ages of 18-38 who underwent a heart operation and their life experiences. This research will focus on these life events and the paradigm of these women being raised as "heart sick," and consequently lacking self-esteem (Frigiola, Bull, & Wray, 2014; Hickey et al., 2012). Most qualitative studies focusing on the quality of life compare men and women, completely ignoring women's body image and the experience of womanhood (Hickey et al., 2012; Hövels-Gürich et al., 2007; Sarikouch, et al., 2013). This study aims to focus on women's stories about their life experiences and the influence of surgery(ies) on their daily life using an the qualitative phenomenological approach.

NCT ID: NCT02905929 Completed - Sedentary Lifestyle Clinical Trials

Trial to Reduce Sitting Time in Postmenopausal Latina Women at Increased Risk for Heart Disease

Start date: April 1, 2017
Phase: N/A
Study type: Interventional

Project 2 of the University of California, San Diego (UCSD) American Heart Association (AHA) Women's Health Program will assess 3-month changes in sitting time, standing time, physical activity and blood pressure in a randomized control trial (RCT). This 2-arm RCT will occur in the community with post menopausal Latina women (N=250) who spend at least 8 hrs/day sitting and have increased risk for cardiovascular disease through high BMI and other cardiometabolic risk factors. Women will be identified through the San Ysidro Health Center and assessed at the South Bay Latino Research Center.

NCT ID: NCT02898090 Completed - Atrial Fibrillation Clinical Trials

Development and Validation of Automated Indicators on the Appropriateness of Oral Anticoagulant Prescriptions

PACHA
Start date: April 28, 2018
Phase:
Study type: Observational

This research focuses on the development and validation of indicators on the appropriateness of oral anticoagulant prescriptions. The investigators want to propose transferable tools to other healthcare institutions to allow automated construction of indicators as part of a structured approach to improve future practices. The main objective of the study is to develop indicators on the appropriateness of oral anticoagulant prescriptions in adult medicine automated from the hospital information system and to assess their criterion validity.

NCT ID: NCT02897323 Recruiting - Clinical trials for Congenital Heart Disease

Northwest Adult Congenital Heart Disease Observatory

CARL
Start date: November 14, 2016
Phase: N/A
Study type: Observational

The incidence of congenital heart disease is about 8 per thousand live births. Thanks to advances in cardiac surgery, 90% of children born with heart defects reach adolescence and adulthood. Congenital heart defects are the leading cause of heart disease in young adults and expectant mothers in Western countries. The number of patients increases continuously as life expectancy increases. An increasing number of patients with complex heart defects survive to adulthood. The medico-surgical management of this highly specialized growing number of patients is difficult and requires a multidisciplinary collaboration. In France, an estimated 200,000 patients the number of carrier patients with congenital heart disease. Half of them will require monitoring, medical procedures, catheterizations and/or surgical re-intervention. No objective demographic data are currently available on the French patients. So, the investigators decided to set up an epidemiological project to better understand this cohort of patients. The main objective of this project is to obtain accurate epidemiological data needed to adapt the supply of care.