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Heart Diseases clinical trials

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NCT ID: NCT06468787 Completed - GYN Disorders Clinical Trials

Kosmos Anatomical Object Labeling and View Identification Pivotal Study

Start date: February 7, 2024
Phase: N/A
Study type: Interventional

This is a multi-site, multi-group study that obtained two sets of ultrasound scans from all enrolled participants. Participants underwent limited ultrasound scanning by both cardiac sonographers and abdominal sonographers. Algorithm's performance on the view identification task and the object labeling task is computed.

NCT ID: NCT06467513 Recruiting - Heart Diseases Clinical Trials

To Investigate the Effect of Esketamine Hydrochloride on Pulmonary Complications

Start date: January 1, 2024
Phase: Phase 4
Study type: Interventional

The objective of this study was to evaluate the effect of esketamine on intraoperative hemodynamics in patients with heart valve replacement and to mitigate postoperative pulmonary complications

NCT ID: NCT06464354 Completed - Clinical trials for Ischemic Heart Disease

Comparison of the Mammary Harvesting Technique

Start date: June 1, 2023
Phase:
Study type: Observational

The skeletonization technique of left internal artery (LIMA) harvesting is reported as more spar-ing to the vascular supply of the sternum. Some studies report a greater length and greater flow of the graft additionally. The aim of our study was to measure the difference in post-op sternal blood supply compared to the pedicle harvesting technique and to measure the length and flow of the LIMA graft.

NCT ID: NCT06455644 Recruiting - Clinical trials for Cardiovascular Diseases

Accuracy of LAA Occluder Size Selection: CT vs. DSA During Combined AF Ablation and LAA Occlusion

Start date: July 2024
Phase: N/A
Study type: Interventional

This study is a prospective, multi-center, randomized controlled trial. The subjects are patients scheduled to undergo a combined procedure of atrial fibrillation (AF) ablation and left atrial appendage (LAA) occlusion. After signing the informed consent form, the subjects will be randomly assigned to either the cardiac Computed Tomography (CT) group or the Digital Subtraction Angiography (DSA) group. The operator will select the appropriate LAA occluder size for implantation based on different measurement methods. All subjects will undergo clinical follow-up before discharge and at 3 months postoperatively, as well as telephone follow-up 1-5 years after the surgery.

NCT ID: NCT06455020 Not yet recruiting - Clinical trials for Ventricular Tachycardia

Catheter Ablation of Haemodynamically Not-tolerated Electrical Storm in Structural Heart Disease

Start date: July 1, 2024
Phase: N/A
Study type: Interventional

This is a multi-center, parallel-group, randomized, open-label trial evaluating the clinical outcome and efficacy of emergency catheter ablation versus conventional stepped-care strategies in patients with haemodynamically not-tolerated ventricular tachycardia (VT).

NCT ID: NCT06450561 Recruiting - Clinical trials for Acute Coronary Syndrome

Adherence to Secondary Prevention Guidelines for Cardiovascular Risk

Start date: March 1, 2024
Phase:
Study type: Observational

The present observational study aims to determine the degree of adherence to the recommendations of clinical guidelines regarding the prevention of cardiovascular complications in patients hospitalized due to a cardiovascular event.

NCT ID: NCT06449469 Recruiting - Clinical trials for Cardiovascular Diseases

The Nordic Aortic Valve Intervention Trial 4 (NOTION-4)

NOTION-4
Start date: May 1, 2021
Phase: N/A
Study type: Interventional

A randomized clinical trial investigating the incidence and temporal dynamics of subclinical leaflet thickening by cardiac CT in transcatheter bioprosthetic aortic valves in patients randomised to different anti-thrombotic strategies. Additionally, this study aims to examine a possible association between HALT and thromboembolic events.

NCT ID: NCT06445231 Not yet recruiting - Heart Failure Clinical Trials

Echocardiography in Nursing Home

ECHOGER
Start date: June 1, 2024
Phase: N/A
Study type: Interventional

The study seeks to explore the implementation characteristics (acceptability, appropriateness, feasibility, adoption, fidelity, penetration, implementation cost and sustainability) of systematic echocardiography in nursing homes and its impact on rates of heart failure flare-up and unscheduled hospitalization at 12 months among included nursing homes.

NCT ID: NCT06438159 Not yet recruiting - Cardiac Disease Clinical Trials

Impact of Mindfulness-Based Stress Reduction Meditation Practice on Patients After Cardiac Rehabilitation.

CARDIO-MBSR
Start date: September 1, 2024
Phase: N/A
Study type: Interventional

Cardiac rehabilitation is a major component of treatment for patients suffering from coronary pathology revealed by myocardial infarction or acute coronary syndrome warranting transluminal coronary angioplasty, as well as in the aftermath of cardiac surgery. A significant proportion of patients in this situation (40%) suffer from varying degrees of anxiety and depression, which are difficult to treat. These impair their quality of life and can make it more difficult for them to take part in the rehabilitation program, compromising the results that can be expected. Finally, they are often associated with lax compliance with medical treatment, less control of risk factors and less regular exercise. Cardiac rehabilitation teams are well aware of this anxiety-depressive picture, and various therapies such as sophrology, relaxation and yoga have been proposed as alternatives to conventional medical treatments to help patients through this period. Among these alternatives is the concept of "Mindfulness-Based Meditation", based on the Mindfulness-Based Stress Reduction (MBSR) protocol described by Dr. JKabat Zinn. It has been the subject of several prospective randomized studies, which have demonstrated that it is suitable for the management of patients in this situation, and that it has measurable beneficial effects on their sense of well-being. To our knowledge, the MBSR program used in cardiac rehabilitation has never been the subject of a randomized comparative study in France to assess its effectiveness on medium- and long-term anxiety-depressive disorders. This is the objective of this study.

NCT ID: NCT06434207 Not yet recruiting - Clinical trials for Congenital Heart Disease

Extracellular Vesicle Micro RNA Profiling in Congenital Heart Disease: Fetal-Maternal Regulation in Neonatal Thrombosis

EVmiRNA
Start date: June 1, 2024
Phase:
Study type: Observational

Newborns with congenital heart disease (CHD) are at increased risk of developing postpartum and postoperative blood clots after cardiac surgery. The molecular mechanisms that are responsible for the clotting profile predisposing children to blood clots in the early stages of life are currently not well described. The goal of this proposal is to prospectively collect plasma samples from ten (10) neonates with antenatal diagnosis of severe congenital heart disease (CHD) to better understand mechanisms responsible for abnormal clotting in the perioperative period.