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Heart Arrest clinical trials

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NCT ID: NCT05133869 Recruiting - Clinical trials for Cognitive Impairment

Brain Outcome After Cardiac Arrest - Intervention

BROCA-i
Start date: April 21, 2022
Phase: N/A
Study type: Interventional

People who suffered a cardiac arrest are often have cognitive impairments. In this study the investigators test the effectiveness of an intervention, combining direct training and metacognitive training, in a single case experimental design (SCED).

NCT ID: NCT05132387 Recruiting - Clinical trials for Out-Of-Hospital Cardiac Arrest

Wroclaw Out-Of-Hospital Cardiac Arrest Registry

WOHCA
Start date: October 25, 2021
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to assess the efficacy of institutionalized care program of patients with out-of-hospital cardiac arrest.

NCT ID: NCT05131854 Recruiting - Spine Surgery Clinical Trials

Incidence , Risk Factors and Outcomes of Haemodynamic Instability and Cardiac Arrest During Spine Surgery

Start date: November 25, 2021
Phase:
Study type: Observational

Risk factors for cardiac arrest during spine surgery have been well defined, including lumbar fusion, age over 65 years, obesity, cardiovascular disease, ethnicity and ASA status. Bradycardia and asystole have been described under general anaesthesia in combined surgical cohorts: Proposed mechanisms include unopposed parasympathetic activation, enhanced vasovagal response to decreased venous return, and psychiatric stressors. The investigators prospectively will review patients candidates for spine surgery to explore potential incidence, contributory factors and outcomes to unexpected transient intraoperative haemodynamic instability, arrhythmia, and cardiac arrest during spine surgery as these data are needed to aid risk stratification and improve decision making for spine care teams.

NCT ID: NCT05113706 Enrolling by invitation - Clinical trials for Out-Of-Hospital Cardiac Arrest

Does Bystanders Emotional State Influence Dispatcher-assisted Cardiopulmonary?Resuscitation

Start date: September 1, 2018
Phase:
Study type: Observational

The study aims to investigate bystanders' emotional stress state in out-of-hospital cardiac arrest (OHCA) emergency calls and the association with the quality of dispatcher-assisted cardiopulmonary resuscitation (DA-CPR).

NCT ID: NCT05079724 Not yet recruiting - Heart Diseases Clinical Trials

Acute Kidney Injury After Cardiac Surgery

Start date: November 1, 2021
Phase:
Study type: Observational

The study aims to identify the Following: - 1. incidence and mortality of cardiac Surgery associated -AKI based on the new consensus diagnostic systems of KDIGO (Kidney Disease Improving Global Outcomes). 2. use of biomarkers for the early detection of clinical and subclinical cardiac Surgery associated-AKI. 3. risk factors and prediction models of cardiac Surgery associated-AKI. 4. optimal cardiac surgical procedures including conventional versus minimally invasive approaches, on-pump versus off-pump, and optimal management of cardiac surgical support including duration of CPB, perfusion pressure, hemodilution, and hypothermia during CPB. 5. controversial pharmacologic therapies for the prevention and treatment of cardiac Surgery associated-AKI including statins, sodium bicarbonate, and N-acetylcysteine (NAC).

NCT ID: NCT05045729 Active, not recruiting - Clinical trials for Out-Of-Hospital Cardiac Arrest

OHCA Sports in Denmark

Start date: January 1, 2016
Phase:
Study type: Observational

While regular exercise is known to prevent cardiovascular disorders, exercise might also trigger acute cardiac events such as cardiac arrest. This study examines the incidence, prognosis and outcomes of out-of-hospital cardiac arrest (OHCA) related to exercise in the general population of Denmark. This retrospective cohort study examins all OHCAs in the Danish Cardiac Arrest Registry from 2016 to 2019 in Denmark. OHCA related to exercise were identified in the nationwide electronic database and coupled to the patient register. OHCA related to exercise was defined as occurring during or up to one hour after exercise of moderate or vigorous intensity. Descriptive statistics are used together with an adjusted multivariate logistic regression model to assess predefined factors of interest.

NCT ID: NCT05029167 Recruiting - Clinical trials for Mechanical Ventilation

REstrictive Versus LIberal Oxygen Strategy and Its Effect on Pulmonary Hypertension After Out-of-hospital Cardiac Arrest (RELIEPH-study)

RELIEPH
Start date: September 11, 2017
Phase: N/A
Study type: Interventional

Background: For patients with out-of-hospital cardiac arrest (OHCA) at the intensive care unit (ICU), oxygen therapy plays an important role in post resuscitation care. During hospitalisation, a lot of these patients occur with pulmonary arterial hypertension (PAH). Currently a wide oxygen target is recommended but no evidence regarding optimal treatment targets to minimise the prevalence of PAH exists. Methods: The RELIEPH trial is a substudy within the BOX (Blood pressure and OXygenation targets in post resuscitation care) trial. It is a single-center, parallel-group randomised controlled clinical trial. 300 patients with OHCA hospitalised at the ICU are allocated to one of the two oxygenation interventions, either a restrictive- (9-10 kPa) or liberal (13-14 kPa) oxygen target both within the recommended range. The primary outcome is the fraction of time with pulmonary hypertension (mPAP >25 mmHg) out of total time with mechanical ventilation. Secondary outcomes are: length of ICU stay among survivors, lactate clearance, right ventricular failure, 30 days mortality and plasma brain natriuretic peptide (BNP) level 48 hours from randomisation. Discussion: This study hypothesises that a liberal target of oxygen reduces the time with PAH during mechanical ventilation compared to a restrictive oxygen target in patients with OHCA at the ICU. When completed, this study hopes to provide new knowledge regarding which oxygen target is beneficial for this group of patients.

NCT ID: NCT05023616 Completed - Education Clinical Trials

Evaluation of Efficacy of Online Real-time Home CPR Training Program

Start date: August 26, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of a real-time home CPR(cardiopulmonary resuscitation) training program. The study participants will be allocated to two different CPR training programs. The intervention group will participate in the real-time home CPR training program while the control group will participate in the conventional CPR training program. The investigators will compare the quality of chest compression between the two study groups. The investigators hypothesize that the new real-time home CPR training program is non-inferior to the preexisting conventional CPR training program.

NCT ID: NCT05011994 Recruiting - Heart Failure Clinical Trials

Maintenance of Physical Activity After Cardiac Rehabilitation

FAIR
Start date: August 30, 2021
Phase: N/A
Study type: Interventional

Physical activity is a key element in cardiac rehabilitation and prevention of cardiovascular mortality and hospitalizations. After cardiac rehabilitation programs end, physical activity levels and participation in continued cardiac rehabilitation declines. The aim of this study is to evaluate the feasibility a mobile health intervention with text messages and behavior change theory in patients with cardiovascular disease for a duration of 3 months after completion of a cardiac rehabilitation program. An intervention consisting of action planning, text messages, and coordinator support is tested in a feasibility trial design with 40 expected participants.

NCT ID: NCT05004610 Not yet recruiting - Cardiac Arrest Clinical Trials

Hypertonic Lactate After Cardiac Arrest

LATTE
Start date: October 1, 2024
Phase: Phase 2
Study type: Interventional

The study is intended to test the hypothesis that sodium lactate infusion after resuscitation from a cardiac arrest will decrease the magnitude of brain damage, as measured by the serum biomarker concentration of NSE.