Healthy Clinical Trial
Official title:
The Effects of Fatigue on Exercise-Induced Hypoalgesia During a Dynamic Resistance Exercise
NCT number | NCT05525403 |
Other study ID # | 2 |
Secondary ID | |
Status | Completed |
Phase | N/A |
First received | |
Last updated | |
Start date | October 28, 2022 |
Est. completion date | April 20, 2023 |
Verified date | April 2023 |
Source | University of Central Florida |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The primary purpose of this study is to compare immediate changes in pain sensitivity (pressure pain threshold) during quiet rest, low fatigue exercise, and high fatigue exercise.
Status | Completed |
Enrollment | 31 |
Est. completion date | April 20, 2023 |
Est. primary completion date | April 20, 2023 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 60 Years |
Eligibility | Inclusion Criteria: - Pain-free - 18-60 years old - Participant can appropriately perform the knee extension exercise (assessed during screening) Exclusion Criteria: - Non-English speaking - Regular use of prescription pain medications - Current or history of chronic pain condition - Currently taking blood-thinning medication - Systemic medical condition known to affect sensation, such as uncontrolled diabetes or neurological conditions - Any contraindication to the application of ice, such as: uncontrolled hypertension (blood pressure over 140/90 mmHg), cold urticaria, cryoglobulinemia, paroxysmal cold hemoglobinuria, circulatory compromise - Known presence of cardiovascular, pulmonary, or metabolic disease - Current use of tobacco products - Not physically ready to exercise without a medical exam as indicated by the Physical Activity Readiness Questionnaire Plus (PAR-Q+) - Surgery, injury, or fracture to the lower back or lower extremity within the past 6 months |
Country | Name | City | State |
---|---|---|---|
United States | University of Central Florida | Orlando | Florida |
Lead Sponsor | Collaborator |
---|---|
University of Central Florida |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | 1-repetition maximum testing | The amount of weight that can be lifted for 1 repetition | Baseline, pre exercise | |
Primary | Change in Pressure Pain Threshold | A digital pressure algometer will be applied to the quadriceps and upper trapezius for two trials each. Participants are instructed to say "stop" or "pain" so the stimulus can be terminated "when the sensation first transitions from pressure to pain" (pain threshold). Participants will rate the pain experienced during the threshold testing using a 101-point numeric pain rate scale (NPRS) anchored with 0= no pain to 100= the most intense pain sensation imaginable immediately following each testing time. | Change from baseline immediately after exercise | |
Secondary | Temporal Summation | Participants will rate a train of 10 heat pulses using the 101-point numerical pain rating scale | Baseline, pre exercise | |
Secondary | Heat Pain Threshold | A thermode will gradually increase temperature. Participants will state when the sensation first becomes painful. | Baseline, pre exercise | |
Secondary | Conditioned Pain Modulation | Pressure pain threshold after an ice water immersion task will be measured. | Baseline, pre exercise | |
Secondary | International Physical Activity Questionnaire Short Form | This is a self-report measure of physical activity that provides data regarding health-related physical activity. | Baseline, pre exercise | |
Secondary | Pittsburgh Sleep Quality Index | This is a 10-item questionnaire in which individuals respond to statements regarding sleep quality. A higher score indicates a worse sleep quality. | Baseline, pre exercise | |
Secondary | Pain Catastrophizing Scale | This is a 13-item questionnaire in which individuals respond to a statement on a five point scale from 0 to 4. Higher scores indicate higher pain catastrophizing levels. | Baseline, pre exercise | |
Secondary | Fear of Pain Questionnaire 9 | This is a 9-item questionnaire in which individuals respond to a statement on a five point scale from 1 to 5. Higher scores indicate higher fear of pain. | Baseline, pre exercise | |
Secondary | Pain Anxiety Symptom Scale | This is a 20-item questionnaire in which individuals respond to a statement on a six point scale from 0 to 5. Higher scores indicate higher pain-related anxiety. | Baseline, pre exercise | |
Secondary | Brief Resilience Scale | This is a 6-item questionnaire in which individuals respond to a statement on a five point scale from 1 to 5. Higher scores indicate greater resilience. | Baseline, pre exercise | |
Secondary | Preference for and Tolerance of the Intensity of Exercise Questionnaire | This is a 16-item questionnaire in which individuals respond to a statement on a five point scale from 1 to 5. Higher scores indicate lower tolerance for the intensity of exercise. | Baseline, pre exercise |
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