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Respiratory Muscle Fatigue at Different Breathing Modes

Healthy Clinical Trial

Official title:
Does Inspiratory Pressure Wave Form Influence Respiratory Muscle Fatigue and Metabolism During Resistive Breathing

Clinical Trial Summary

The study aims at investigating if time to respiratory muscle fatigue and metabolism are influenced by the pressure wave form mode applied during resistive breathing.

Clinical Trial Description

In healthy subjects fitted with a nasogastric double balloon catheter and breathing at a resistance, the investigators will measure time to failure, Borg ratings, VO2, VCO2, flow, esophageal-, gastric- and airway-pressure. This will be done during breathing at either a square wave or triangle wave pressure waveform, in random order and trials separated by >two days. Further respiratory muscle fatigue will be investigated pre and post intervention by maximal esophageal pressure generation (voluntary and with cervical magnetic stimulation). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05393115
Study type Interventional
Source Aalborg University
Contact
Status Recruiting
Phase N/A
Start date October 1, 2021
Completion date December 1, 2022
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