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GLS-5310 Vaccine in Healthy Volunteers for the Prevention of SARS-CoV-2 (COVID-19)

Healthy Clinical Trial

Official title:
Phase I Study of the Safety, Tolerability and Immunogenicity of GLS-5310 DNA Vaccine Against SARS-CoV-2

Clinical Trial Summary

Phase I study of the safety, tolerability and immunogenicity of GLS-5310 DNA vaccine against SARS-CoV-2 (COVID-19)

Clinical Trial Description

This Phase I, randomized, placebo-controlled, dose-ranging, single-blind study will assess the safety, tolerability, and immunogenicity of GLS-5310 DNA vaccine administered intradermally (ID) with or without concomitant intranasal (IN) administration of GLS-5310. Vaccine delivered ID will either be performed by Mantoux injection and followed by suction applied to the skin surface using the Gene-Derm device or Mantous injection alone without applied suction. Vaccine delivered IN will be administered using the MAD300 atomizer. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05085639
Study type Interventional
Source GeneOne Life Science, Inc.
Contact Medical Monitor
Phone 610-707-5671
Email jmaslow@genels.us
Status Not yet recruiting
Phase Phase 1
Start date November 2021
Completion date December 2022
View Details
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