Healthy Clinical Trial
Official title:
A Proof of Concept Study to Evaluate Aerosol Generation During Non-Invasive Positive Pressure Respiratory Procedures
Verified date | August 2020 |
Source | Guy's and St Thomas' NHS Foundation Trust |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Currently, a major issue within respiratory medicine is undertaking procedures that generate aerosolisation with the concern of spreading infection, such as the SARS-COV-2/COVID-19 virus. It is anecdotally reported that lung function testing and positive airways pressure devices used in clinical practice are aerosol generating procedures however the data to support this is limited. With the advent of high-speed imaging systems that can capture and quantify particle size and velocity we aim to investigate the aerosol generation in routine non-invasive positive pressure respiratory procedures.
Status | Not yet recruiting |
Enrollment | 10 |
Est. completion date | September 1, 2021 |
Est. primary completion date | September 1, 2021 |
Accepts healthy volunteers | |
Gender | All |
Age group | 18 Years to 80 Years |
Eligibility | Inclusion Criteria: - Age 18-80 years - Healthy subjects with no active medical conditions or previous pneumothorax - Cognitively and linguistically able to follow instructions given in English and provide informed consent Exclusion Criteria: - Significant respiratory, cardiac or neurological conditions or previous pneumothorax - Smoking history greater than 10 pack years - Acute illness at the time of assessment - Allergies to latex, metals or local anaesthetic agents |
Country | Name | City | State |
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n/a |
Lead Sponsor | Collaborator |
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Guy's and St Thomas' NHS Foundation Trust |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Characterisation of aerosolised respiratory droplets | Performed using high-speed imaging and particle size counters | 1 year |
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