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Sex Disparities in Hypoxic Sympatholysis and Impact of Obesity

Healthy Clinical Trial

Official title:
Sex Disparities in Hypoxic Sympatholysis and Impact of Obesity

Clinical Trial Summary

Patients with sleep apnea are at increased risk of developing cardiovascular disease - with women at potentially greater risk than men. Contributing mechanisms are not well understood, but may be related to how women respond to low oxygen and, given over 70% of patients with sleep apnea are obese, the impact of obesity. This project seeks to increase our understanding of mechanisms that may contribute to sex differences in the cardiovascular response to low oxygen with the hope that this knowledge will improve the efficacy of current therapies and support the discovery of novel therapeutics.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04436731
Study type Interventional
Source University of Missouri-Columbia
Contact Jacqueline K Limberg, Ph.D.
Phone 573-882-2544
Email limbergj@missouri.edu
Status Recruiting
Phase Early Phase 1
Start date December 9, 2020
Completion date June 30, 2025
View Details
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