Healthy Clinical Trial - Effect of Exenatide on Cortisol Secretion

Status Completed

Clinical Trial Summary

The primary aim of the study is to describe the effect of single dose of 10 micrograms (μg) exenatide given subcutaneously (s/c) on cortisol secretion. Secondary outcomes involve ACTH and glucose levels.

Clinical Trial Description

Exenatide is a short-acting Glucagon-Like Peptide receptor 1 (GLP-1 R) agonist.

The clinical trial is conducted in10 healthy volunteers. Each subject receives one dose of subcutaneous exenatide (10 μg). After that, hormonal and physiological changes are measured during two hours. The blood samples are taken in 30-minute intervals.

The primary endpoint is peak value of cortisol achieved during the 2 hours after drug administration. ;

Study Design

Related Conditions & MeSH terms

Healthy

Clinical Trial Details

NCT number	NCT03160261
Study type	Interventional
Source	University of Tartu
Contact
Status	Completed
Phase	Phase 4
Start date	September 7, 2017
Completion date	December 28, 2017

View Details

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