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Clinical Trial Summary

The primary aim of the study is to describe the effect of single dose of 10 micrograms (μg) exenatide given subcutaneously (s/c) on cortisol secretion. Secondary outcomes involve ACTH and glucose levels.


Clinical Trial Description

Exenatide is a short-acting Glucagon-Like Peptide receptor 1 (GLP-1 R) agonist.

The clinical trial is conducted in10 healthy volunteers. Each subject receives one dose of subcutaneous exenatide (10 μg). After that, hormonal and physiological changes are measured during two hours. The blood samples are taken in 30-minute intervals.

The primary endpoint is peak value of cortisol achieved during the 2 hours after drug administration. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03160261
Study type Interventional
Source University of Tartu
Contact
Status Completed
Phase Phase 4
Start date September 7, 2017
Completion date December 28, 2017

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