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Single-Ascending Dose Study of BIIB054 in Healthy Participants and Early Parkinson's Disease

Healthy Clinical Trial

Official title:
A Phase 1 Randomized, Double-Blinded, Placebo-Controlled Single-Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of BIIB054 in Healthy Subjects and Subjects With Early Parkinson's Disease

Clinical Trial Summary

The primary objective of the study is to evaluate the safety and tolerability of a range of single BIIB054 doses, administered as a single intravenous (IV) infusion, in healthy participants and participants with early Parkinson's disease (PD). Secondary objectives of the study are to assess the serum pharmacokinetics (PK) profile of BIIB054 after single-dose administration and to evaluate the immunogenicity of BIIB054 after single-dose administration.

Clinical Trial Description

Only healthy participants will be enrolled in Cohorts 1 through 6. Only participants with early PD will be enrolled in Cohort 7 ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02459886
Study type Interventional
Source Biogen
Contact
Status Completed
Phase Phase 1
Start date July 1, 2015
Completion date November 20, 2017
View Details
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