Central Blood Pressure in Adolescents and Young Adults

Healthy Clinical Trial

Official title:

Diurnal Variation of Central Blood Pressure in Adolescents and Young Adults and Association With Indices of Asymptomatic Target-organ Damage

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02222077
• Other study ID #: Central BP-TOD
• Status: Recruiting
• Phase: N/A
• First received: August 15, 2014
• Last updated: September 13, 2017
• Start date: July 2014
• Est. completion date: February 2018

Study information

• Verified date: September 2017
• Source: University of Athens
• Contact: George S Stergiou, Professor of Medicine
• Phone: +302107763117
• Email: gstergi[@]med.uoa.gr
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study aims to investigate in adolescents and young adults:

• the 24h diurnal variation of ambulatory central blood pressure

• the association of central compared to peripheral blood pressure with indices of asymptomatic target-organ damage

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 150
• Est. completion date: February 2018
• Est. primary completion date: February 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 12 Years to 25 Years

Eligibility

Inclusion Criteria:

• Adolescents and young adults (age range 12-25 years)

Exclusion Criteria:

• Subjects with any acute or significant chronic disease, with evidence of secondary hypertension, or on regular drug treatment will be excluded

Related Conditions & MeSH terms

• Healthy
• Hypertension

Locations

Country	Name	City	State
Greece	Hypertension Center, 3rd University Department of Medicine, Sotiria Hospital	Athens	Attica

Sponsors (1)

Lead Sponsor	Collaborator
University of Athens

Country where clinical trial is conducted

Greece, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Correlation coefficients (r) between 24h ambulatory central blood pressure and indices of target-organ damage	Correlation coefficients (r) will be determined for the relationship between central blood pressure and indices of target-organ damage (left ventricular mass index, carotid intima-media thickness, pulse wave velocity). Also, these coefficients will be compared with z-statistic with the respective ones for the peripheral blood pressure.	Assessment of each individual will require up to 3 days