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NCT00291993 Clinical Trial

Vasoactive Hormones During the Night in Patients With Obstructive Sleep Apnea and Healthy Controls.

Healthy Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00291993
Other study ID # MED.RES.HOS.2004.01.PHH
Secondary ID
Status Completed
Phase Phase 4
First received February 13, 2006
Last updated April 17, 2008
Start date January 2004

Study information
Verified date April 2008
Source Regional Hospital Holstebro
Contact n/a
Is FDA regulated No
Health authority Denmark: Ethics Committee
Study type Observational

Clinical Trial Summary

Obstructive sleep apnea syndrome is complicated by considerable cardiovascular morbidity and mortality, at least partly due to hypertension. Nocturnal hypoxia, hypercapnia and acidosis stimulate chemoreceptors and presumably increased secretion of vasoactive hormones which might be responsible for hypertension in these patients.

The aim of this study is to measure the secretion of vasoactive hormones at night and to analyse the relationship between vasoactive hormones, oxygen saturation and the blood pressure at night.

Recruitment information / eligibility
Status Completed
Enrollment 0
Est. completion date
Est. primary completion date
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 20 Years to 65 Years
Eligibility Inclusion Criteria:

Male and female Age 20-65 Obstructive sleep apnea

Exclusion Criteria:

Drug or alcohol abuse Pregnancy or breast feeding Cancer Clinical signs or history of disease in the heart, lungs, kidney or endocrine organs Abnormal laboratory tests Albuminuria or glucosuria Aterial hypertension for healthy subjects

Study Design

Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
Denmark Department of Medical Research Holstebro
Denmark Department of Medical Research, Holstebro Hospital Holstebro Ringkoebing County
Denmark Holstebro Hospital, Department of Medical Research Holstebro

Sponsors (1)
Lead Sponsor Collaborator
Regional Hospital Holstebro

Country where clinical trial is conducted

Denmark, 

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