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Head and Neck Tumor clinical trials

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NCT ID: NCT06016335 Completed - Hearing Loss Clinical Trials

MRI-based Synthetic CT Images of the Head and Neck

Start date: September 22, 2022
Phase: N/A
Study type: Interventional

In case of surgical procedures in the head and neck region, MRI in combination with CT of the bone is often the standard modality to visualise bony landmarks for planning, navigation and risk assessment. An important downside of a CT scan is the associated radiation exposure, especially in children. An additional downside is the sedation or general anaesthesia needed for both the MRI and CT scan session in very young children. These downsides could be removed if the CT scan can be substituted by an MRI sequence that can provide the same information as CT. This project aims to determine the feasibility of recreating CT like images of the craniofacial bones from MRI images using machine learning techniques.

NCT ID: NCT05183243 Recruiting - Colorectal Cancer Clinical Trials

Dose Finding Study of GH21 in Adult Patients With Advanced Solid Tumors

Start date: February 20, 2022
Phase: Phase 1
Study type: Interventional

Evaluate the safety and tolerability of GH21 in patients with advanced solid tumors. Estimate the maximum tolerated dose (MTD) in patients with advanced solid tumors.

NCT ID: NCT05053230 Recruiting - Clinical trials for Head and Neck Cancer

A Study Evaluating the Integrative Medicine at Home (IM@HOME) Program in People With Cancer

IMPROVE
Start date: September 20, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to find out whether the Integrative Medicine at Home (IM@Home) program can help reduce patients' symptoms (such as tiredness, pain, or insomnia) and improve their satisfaction with treatment for their disease. The IM@Home program offers virtual (online rather than in-person) group classes focusing on mind-body practice. Mind-body practice is a health practice that combines mental focus, controlled breathing, and body movements to help relax the body and mind.

NCT ID: NCT04334239 Completed - Breast Cancer Clinical Trials

Effectiveness of Care in Certified Cancer Centres in Germany

WiZen
Start date: May 1, 2017
Phase:
Study type: Observational

Assessment of the effectiveness of care in certified cancer centres for eight cancer entities via a retrospective cohort study based on secondary data from statutory health insurance funds and population-based clinical cancer registries.

NCT ID: NCT04075305 Recruiting - Breast Cancer Clinical Trials

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

MOMENTUM
Start date: February 1, 2019
Phase:
Study type: Observational [Patient Registry]

The Multi-OutcoMe EvaluatioN of radiation Therapy Using the Unity MR-Linac Study (MOMENTUM) is a multi-institutional, international registry facilitating evidenced based implementation of the Unity MR-Linac technology and further technical development of the MR-Linac system with the ultimate purpose to improve patients' survival, local, and regional tumor control and quality of life.

NCT ID: NCT01228448 Completed - Brain Tumor Clinical Trials

In-Room PET in Proton Radiation Therapy

Start date: October 2010
Phase: N/A
Study type: Interventional

The investigational part of this study is using a mobile PET/CT scanner to take images of the participants tumor immediately after they are treated with proton radiation. This allows the participant to be treated and imaged on the same bed. The information obtained may improve the accuracy of treatment and may help to minimize the dose delivered unnecessarily to healthy tissue.

NCT ID: NCT00406289 Completed - Head and Neck Tumor Clinical Trials

Trial of Adaptive 18F-FDG-PET Biological Intensity-modulated Radiotherapy (BG-IMRT) in Patients With Head and Neck Tumor

Start date: November 2006
Phase: Phase 1
Study type: Interventional

This study will evaluate the feasibility of higher and prolonged dose escalation concentrated in the intra-tumoral regions which are FDG-avid after two weeks of radiotherapy.