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Clinical Trial Summary

In this study, patients diagnosed with a pathology-proven malignancy of the head and neck will receive a routine clinical activity of 18F-FDG ((18)F-luorodeoxyglucose) before undergoing standard of care surgical resection of the malignancy. Following the resection, the 18F-FDG-infused malignancy will be investigated utilizing a novel high-resolution Positron Emission Tomography (PET) and Computed Tomography (CT) scan. Slicing of the malignancy will be followed by additional PET/CT-scanning and autoradiography of the sliced specimen. The results found during image analysis will be compared to the results of the gold standard of histopathology. As this is no approved way of assessing the tumour's margin, the conclusion of the scan will not be used as a method for changing the patients' treatment.

Clinical Trial Description


Study Design

Related Conditions & MeSH terms

NCT number NCT05068687
Study type Interventional
Source University Hospital, Ghent
Contact Jens M Debacker, MD
Phone +329 332 39 90
Email [email protected]
Status Recruiting
Phase N/A
Start date August 28, 2020
Completion date December 31, 2021

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