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Feasibility of Holmium-166 Micro Brachytherapy in Head and Neck Tumors — HIT  

Head and Neck Neoplasms Clinical Trial

Official title:
Feasibility of Holmium-166 Microspheres for Selective Intra-tumoural Treatment in Head and Neck Cancer: Biodistribution and Safety in Patients With Malignancy of the Tongue

Clinical Trial Summary

The main objective is to establish the feasibility of 166-Holmium microspheres for intratumoral injections in oral squamous cell carcinoma (OSCC) of the tongue.

Participants will receive intratumoral injections with a low radioactive 166-Holmium microspheres followed by surgical resection

Clinical Trial Description

166-Holmium microspheres poly lactic acid microspheres are currently used in selective internal radiation therapy. These microspheres emits beta radiation. The majority of the radiation dose will be absorbed within 3.2 mm with a maximum penetration in tissue of 9 mm. Therefore this can result in a high local tumor ablative dose with minimal dose to healthy adjacent tissue. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02975739
Study type Interventional
Source UMC Utrecht
Contact
Status Terminated
Phase N/A
Start date September 2016
Completion date September 5, 2018
View Details
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