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Goiter clinical trials

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NCT ID: NCT03072654 Completed - Goiter, Nodular Clinical Trials

Tracheal Anatomy After Thyroidectomy

Start date: November 1, 2014
Phase: N/A
Study type: Observational

The investigators aimed at investigating the effects of thyroidectomy on tracheal anatomy and airflow in patients with benign nodular goiter, employing a prospective observational study. Magnetic resonance images of the neck and respiratory flow-volume curves were performed prior to and six months following surgery. Tracheal and thyroid volumes, smallest cross-sectional area of the trachea (SCAT), tracheal narrowing, tracheal deviation and tracheal encirclement by the thyroid were evaluated. Through flow-volume curves respiratory function, including both in- and expiration, was evaluated.

NCT ID: NCT02710799 Completed - Obesity Clinical Trials

Evaluation of the Effects of Teleconsultations on a Endocrinology Referral List

Start date: June 2015
Phase: N/A
Study type: Interventional

The aim of this study is evaluate the effects of telephone teleconsultations to primary care physicians (compared to the state's referral protocol) in the referrals waiting list for endocrinological appointments.

NCT ID: NCT02651818 Completed - Goiter Clinical Trials

Changes in Quality of Life Following Surgical Treatment of Benign Non-toxic Goiter

SOLOIST
Start date: October 30, 2014
Phase:
Study type: Observational

The aim is to investigate the influence of surgical treatment on benign non-toxic goiter on the disease specific quality of life evaluated 6 months after thyroid surgery. All investigations follow already scheduled treatments.

NCT ID: NCT02194920 Completed - Thyroid Carcinoma Clinical Trials

Parathyroid Reimplantation in Forearm Subcutaneous Tissue During Thyroidectomy: a Simple Way to Avoid Ipoparathyroidism and Evaluate Graft Function

Start date: October 2014
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate safety and effectiveness of normal parathyroid tissue reimplantation in forearm subcutaneous tissue in case of accidental removal of parathyroid gland during thyroid surgery.

NCT ID: NCT01771523 Completed - Goiter Clinical Trials

Is the Use of Drain for Thyroid Surgery Realistic?

Start date: January 2010
Phase: N/A
Study type: Interventional

Background : The use of suction drains in thyroid surgery is common practice in order to avoid haematoma or seroma, as well as to identify promptly the onset of haemorrhaging that might compromise the patient's airway. The aim of this study to determine the effects of routine drainage compared to no drainage in thyroidectomy patients. Study Design : Total of 400 patients who undergoing total thyroidectomy or lobectomy for thyroidal disorders will be randomly allocated to be drained or not. Postoperative ultrasonographic (USG) neck examination will be performed for all patients on postoperative 24th hour by the same ultrasonologist each time. Postoperative pain, complications and hospital stay will be recorded. The statistical analysis will be performed and p<0,05 will be accepted as an important statistical value (SPSS 16.0 for Windows).

NCT ID: NCT01588288 Completed - Goiter, Nodular Clinical Trials

Galectin 3 Dosage in Diagnosis of Nodular and Multinodular Goiter

Galectins
Start date: September 2012
Phase: N/A
Study type: Interventional

The investigators will dose galectin 3 in plasma and water rinse of the needle aspiration biopsy in patients with thyroid nodules. The investigators aim to show that preoperative dosage of the galectin 3 could provide good diagnosis of malignant versus benign thyroid cancer.

NCT ID: NCT01408368 Completed - Thyroid Clinical Trials

Subtotal Versus Total Thyroidectomy for Graves' Disease

Start date: January 2000
Phase: N/A
Study type: Interventional

The extent of thyroid resection in Graves' disease remains controversial. The aim of this study was to evaluate long-term results of bilateral subtotal thyroidectomy versus total thyroidectomy in patients with Graves' ophthalmopathy.

NCT ID: NCT01395134 Completed - Thyroid, Clinical Trials

Visualization Versus Neuromonitoring of the External Branch of the Superior Laryngeal Nerve During Thyroidectomy.

Start date: September 2009
Phase: N/A
Study type: Interventional

Injury to the external branch of the superior laryngeal nerve (EBSLN) during thyroidectomy results in lowered fundamental frequency of the voice and worsened voice performance in producing high-frequency sounds. It remains unclear if use of intraoperative nerve monitoring (IONM) can improve clinical outcome of thyroidectomy in terms of preserved individual voice performance. This study was designed to test that hypothesis.

NCT ID: NCT01384786 Completed - Thyroid Cancer Clinical Trials

The Incidence of Thyroid Cancer in 4474 Patients Treated for Hyperthyroidism or Goiter

Start date: October 2004
Phase: N/A
Study type: Observational

Patients with hyperthyroidism and/or goiter are evaluated with blood samples and scintiscan before they are treated with radioiodine for their thyroid disease. Because the investigators do not get a histologically/final diagnosis the investigators want to make sure, that the patients treated do not have a thyroid cancer when treated. The investigators have found that thyroid cancer is not overlooked.

NCT ID: NCT01349634 Completed - Iodine Deficiency Clinical Trials

The Effects of Iodized Salt on Cognitive Development in Ethiopia

Start date: October 2011
Phase: N/A
Study type: Interventional

Many school children in Ethiopia and their mothers are known to be iodine deficient. Prevalence in the Amhara region is around 29%. Micronutrient Initiative, a development organization based in Ottawa, plans to help iodize the salt by providing iodization machines and iodine to the salt producers in Lake Afdira where salt is produced and distributed to the population of Ethiopia. Although it is generally assumed that iodine is important for cognitive development, very few studies examining the effects of iodized salt have been conducted. Studies using a single dose of iodine capsules with children 6 to 12 years showed mixed outcomes with approximately 25% yielding positive outcomes for the intervention children. Sixty districts in Amhara will be randomly selected and randomly assigned so that half receive early delivery of iodized salt. Approximately 6200 mothers and their children 6-, 18-, or 60-months old will be recruited from 1-2 villages in each of the 60 districts, with the help of government-paid Health Extension Workers, for a 12-mo longitudinal study starting in May 2011, prior to the introduction of iodized salt. These same mothers and children will be visited 12 months later for repeated measures. Measures include nutritional status such as height and hemoglobin, along with iodine sufficiency (e.g., goitre, urinary iodine, thyroglobulin), and child development (Bayley Scales of Infant and Toddler Development III, Wechsler Preschool and Primary School Intelligence test for older children). Comparisons will be made within and between groups to determine whether iodized salt has an effect on children's mental development.