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Glaucoma clinical trials

View clinical trials related to Glaucoma.

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NCT ID: NCT06139523 Recruiting - Glaucoma Clinical Trials

Optimize Pediatric OCT Imaging

Start date: January 24, 2024
Phase:
Study type: Observational

Handheld optical coherence tomography (OCT) has become an important imaging modality to evaluate the pediatric retina. The objective of this pilot study is to compare a new contact OCT system (Theia Imaging) with an investigational noncontact OCT system (Duke Biomedical Engineering) to assess their ability to image the pediatric retina. The investigators hypothesize that the contact OCT system is superior in imaging larger areas of the retina (larger field-of-view), while it has similar resolution to image the retina substructures (non-inferior image quality).

NCT ID: NCT06135727 Enrolling by invitation - Glaucoma Clinical Trials

Screening Protocol

Start date: November 7, 2023
Phase: N/A
Study type: Interventional

The objective of this study is to collect data for the development and validation a screening process using aggregate data. In this study, data collection will encompass both retrospective and prospective approaches across multiple sites in the United States.

NCT ID: NCT06128720 Recruiting - Glaucoma Clinical Trials

Hyperbaric Oxygen Therapy for Optic Neuropathies

HBOT
Start date: November 1, 2022
Phase: N/A
Study type: Interventional

The purpose of the study is to evaluate the neuroprotective efficacy of hyperbaric oxygen for the treatment in patients with optic neuropathy.

NCT ID: NCT06124521 Not yet recruiting - Glaucoma Clinical Trials

Community Based Treatment for (ComBaT) Glaucoma

Start date: May 2024
Phase: N/A
Study type: Interventional

The purpose of this research is to evaluate if intervention and education can change the behavior of someone's willingness to see an eye care provider to prevent blindness and glaucoma. The researchers are investigating if adding additional resources improves participant access to care.

NCT ID: NCT06120842 Recruiting - Cataract Clinical Trials

Evaluation of the Bimatoprost Implant System Used in Combination With the SpyGlass Intraocular Lens Compared to Timolol Ophthalmic Solution

Tigris
Start date: October 13, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

This trial is a randomized study to evaluate and compare two doses of the Bimatoprost Implant System used in combination with the SpyGlass IOL to Timolol Ophthalmic Solution in participants with mild to moderate open-angle glaucoma or ocular hypertension undergoing cataract surgery.

NCT ID: NCT06120621 Completed - Clinical trials for Narrow-Angle Glaucoma

Combined VCST With Phacoemulsification Versus Phacoemulsification in Primary Angle Closure Glaucoma

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

As ab externo metal probe trabeculotomy cannot achieve 360-degree circumferential angle surgery, prolene suture can be used to achieve this without the need for an illuminated microcatheter. In order to combine the advantages of the use of viscoelastic and those of circumferential trabeculotomy, this technique (Visco-Circumferential-Suture- Trabeculotomy "VCST") was previously used successfully in PCG. (7) In the current study , the authors hypothesize that combination of VCST with phacoemulsification in primary angle closure glaucoma patients may have an added affect to phacoemulsification alone in cases with more extent of angle damage and that the injection of a viscoelastic into both ends of the unroofed SC before its cannulation by a polypropylene suture and subsequent circumferential trabeculotomy may facilitate circumferential cannulation of SC and hence the trabeculotomy and increase the success of the technique

NCT ID: NCT06119178 Enrolling by invitation - Glaucoma Clinical Trials

EX-PRESS® P-50 and EX-PRESS® P-200

Start date: November 21, 2023
Phase:
Study type: Observational

The purpose of this Post-Market Clinical Follow-Up (PMCF) study is to assess long term clinical performance and safety outcomes for EX-PRESS Glaucoma Filtration Devices Models P-50 and P-200.

NCT ID: NCT06112431 Not yet recruiting - Clinical trials for Adherence to In-Office Glaucoma Evaluation Appointment

Telehealth-Based Intervention to Detect and Manage Glaucoma Among High-Risk Populations

NYC-SIGHT-2
Start date: September 30, 2024
Phase: N/A
Study type: Interventional

Abundant evidence indicates that vision and eye health disparities exist due to a disproportionate eye disease burden among high-risk populations. Columbia University Department of Ophthalmology clinical researchers designed the New York City SIGHT Study (NYC-SIGHT-2) to evaluate Effectiveness of a Telehealth-Based Intervention to Detect and Manage Glaucoma Among High-Risk Populations in Community Health Settings in Upper Manhattan. The program begins with a telehealth-based eye health screening, optometric exam, eyeglasses, and referral to ophthalmology. The telehealth-based intervention uses patient navigators and peer ambassadors to improve eye care access, utilization, and adherence to in-office glaucoma evaluation appointment compared to Usual Care, while the study also explores the experiences of enrolled participants and program staff as well as cost-effectiveness of the intervention.

NCT ID: NCT06078605 Recruiting - Glaucoma Clinical Trials

Efficacy of Nicotinamide on Retinal Ganglion Cell Functions in Glaucoma Patients

Start date: September 16, 2022
Phase: N/A
Study type: Interventional

Efficacy of Nicotinamide on Retinal Ganglion Cell Functions in Glaucoma Patients : Clinical Trial, Cross-over Design, Double-blind, Placebo-control, Randomized, Single-center Study

NCT ID: NCT06078592 Completed - Glaucoma Clinical Trials

Comparison of Efficacy and Ocular Surface Assessment Between BRIDIN-plus and Combigan in Glaucoma or Ocular Hypertensive

BCT
Start date: October 8, 2021
Phase: Phase 4
Study type: Interventional

Comparison of Efficacy and Ocular Surface Disease Assessment between BRIDIN-plus Eye drops and Combigan Eye drops in Glaucoma or Ocular Hypertensive Patients : Phase 4, Parallel Group Design, Investigator-blind, Active-control, Randomized, Multi-center Trial