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Glaucoma clinical trials

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NCT ID: NCT06355765 Completed - Clinical trials for Glaucoma, Open-Angle

Citicoline & Antioxidants in Glaucoma

Start date: January 10, 2022
Phase:
Study type: Observational [Patient Registry]

To evaluate the long-term effects of oral citicoline, vitamins A, B, C and E, and blackcurrant therapy in patients with primary open-angle glaucoma (POAG) using optical coherence tomography (OCT), OCT angiography (OCTA) and microperimetry parameters.

NCT ID: NCT06252246 Completed - Clinical trials for Primary Angle Closure Glaucoma

The Effect of Phacoemulsification on Intraocular Pressure in Primary Angle Closure Glaucoma (PACG) Patients At Phanat Nikhom Hospital, Chonburi Province

Start date: October 1, 2017
Phase:
Study type: Observational

BACKGROUND: Primary angle closure glaucoma (PACG) is one of a leading cause of blindness worldwide including Thailand. This problem impact to the overall health of people and health care system. Treatment guidelines of each stage is differenced. Therefore, factors that affect to treatment should be explored to plan for taking care patients in the future. OBJECTIVES: The study aimed to examine the effects of cataract surgery by phaco- emulsification on intraocular pressure and to determine the factors associated with intraocular pressure among primary angle closure glaucoma patients.

NCT ID: NCT06247072 Completed - Glaucoma Clinical Trials

TRK-3 Conformance to Standards for Tonometers

Start date: February 2, 2024
Phase:
Study type: Observational

To collect measurements of a new tonometer and show conformance to standards for tonometers.

NCT ID: NCT06237764 Completed - Risk Reduction Clinical Trials

Genetic and Risk Factors in Exfoliation Glaucoma Patients

Start date: January 1, 2014
Phase:
Study type: Observational

Prospective non-randomised cohort study enrolling patients with exfoliation glaucoma. All patients were ophthalmological examined at inclusion. Blood samples were taken for genetic analysis.

NCT ID: NCT06226935 Completed - Clinical trials for Evaluate the Differences in Glaucoma Screening Uptake Among FDRs in Community and Hospital-based

Comparative Analysis of Glaucoma Screening Uptake Among First-Degree Relatives in Community-Based and Hospital-Based Approaches

Start date: January 1, 2022
Phase:
Study type: Observational [Patient Registry]

In conclusion, the study shows that the hospital-based group had a significantly higher screening uptake than the community-based group, reflecting that information from ophthalmologists and registered ophthalmic nurses is more effective and well-received than that from village health volunteers. The study suggests that increasing education and support for village health volunteers could enhance screening uptake. Factors influencing uptake include the age of FDRs, place of residence, education, presenting VA of probands, and treatment of probands. Utilizing this study's findings, spreading knowledge and training health officials at the district and sub-district levels could increase understanding of glaucoma and improve communication with the general public and at-risk groups, potentially increasing the response rate. Additionally, implementing a national free screening glaucoma program for at-risk populations, both in and outside hospitals, and organizing mobile screening units at the district level could be an effective prevention strategy against permanent vision loss from glaucoma.

NCT ID: NCT06184620 Completed - Clinical trials for Primary Angle Closure Glaucoma

Correlation Between Angle Closure Glaucoma Data and Lens Zonule Status

Start date: December 1, 2020
Phase:
Study type: Observational

The goal of this observational study is to discuss the correlation between primary angle-closure glaucoma and the state of the suspended ligament of the lens and the pathogenesis of PACG by measuring the biological data of primary angle-closure glaucoma and observing its anatomical changes.

NCT ID: NCT06158984 Completed - Dry Eye Clinical Trials

Managing Dry Eye in Patients Using Glaucoma Drops

Start date: October 3, 2023
Phase: N/A
Study type: Interventional

A single center randomized controlled trial on managing dry eye signs and symptoms in patients using anti-glaucoma eye drops.

NCT ID: NCT06144918 Completed - Ocular Hypertension Clinical Trials

Phase 2, Placebo-Controlled, Study Assessing the Safety and Ocular Efficacy of SBI-100 Ophthalmic Emulsion in Patients With Elevated Eye Pressure

Start date: November 9, 2023
Phase: Phase 2
Study type: Interventional

The goal of this clinical trial is to test in patients with glaucoma and elevated pressure in the eye. The main questions it aims to answer are: • ability to lower pressure in the eye • safety in the eye and the body of patients with elevated pressure in the eye. Patients will be randomly given either: - 0.5% (5 mg/mL) SBI-100 Ophthalmic Emulsion - 1.0% (10 mg/mL) SBI-100 Ophthalmic Emulsion - Placebo Ophthalmic Emulsion Patients will be tested before starting and will have one drop of the product placed into each eye twice a day for 14 days, by the site and by the patient. At the end of the study, researchers will compare the groups to see if there is a change from before use of SBI-100 Ophthalmic Emulsion to the end of study.

NCT ID: NCT06143943 Completed - Clinical trials for Glaucoma, Angle-Closure

Anterior Segment Anatomic Parameters for Risk Profiling of Primary Angle-closure Glaucoma

Start date: November 22, 2022
Phase:
Study type: Observational

The goal of this observational study is to examine the anterior segment anatomical parameters associated with the scleral spur and cornea for risk profiling of primary angle-closure glaucoma (PACG). The main question it aims to answer is: • Are there new anatomical parameters of the anterior segment of the eye that can be used early for risk profiling for PACG? Researchers will compare PACG and narrow angle groups to see if there are some anatomical parameters that can distinguish the two.

NCT ID: NCT06120621 Completed - Clinical trials for Narrow-Angle Glaucoma

Combined VCST With Phacoemulsification Versus Phacoemulsification in Primary Angle Closure Glaucoma

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

As ab externo metal probe trabeculotomy cannot achieve 360-degree circumferential angle surgery, prolene suture can be used to achieve this without the need for an illuminated microcatheter. In order to combine the advantages of the use of viscoelastic and those of circumferential trabeculotomy, this technique (Visco-Circumferential-Suture- Trabeculotomy "VCST") was previously used successfully in PCG. (7) In the current study , the authors hypothesize that combination of VCST with phacoemulsification in primary angle closure glaucoma patients may have an added affect to phacoemulsification alone in cases with more extent of angle damage and that the injection of a viscoelastic into both ends of the unroofed SC before its cannulation by a polypropylene suture and subsequent circumferential trabeculotomy may facilitate circumferential cannulation of SC and hence the trabeculotomy and increase the success of the technique