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Glaucoma clinical trials

View clinical trials related to Glaucoma.

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NCT ID: NCT05392738 Enrolling by invitation - Lenses, Intraocular Clinical Trials

Visual Function and Patient Satisfaction in Glaucoma or Ocular Hypertensive Patients Undergoing Simultaneous Cataract Surgery and i-Stent Implantation

Start date: June 20, 2022
Phase:
Study type: Observational

New extended depth of focus intraocular lenses (IOLs) are being used in a broader spectrum of patients than trifocal IOLs. The purpose of this study is to evaluate visual improvement after cataract surgery in patients with glaucoma or ocular hypertension undergoing simultaneous cataract surgery with i-Stent implantation with the implantation of a Vivity IOL. Results will be compared with a group of glaucoma or ocular hypertension undergoing isolated cataract surgery with Vivity implantation, as well as with patients with no pathology undergoing cataract surgery and Vivity implantation

NCT ID: NCT05159960 Enrolling by invitation - Ocular Hypertension Clinical Trials

Optimal Treatment Protocol for Selective Laser Trabeculoplasty - Repeat Trial

OSLT-R
Start date: January 10, 2022
Phase: N/A
Study type: Interventional

Glaucoma is a common eye disease that can lead to blindness. The only known way to reduce the rate of disease progression is by reducing the pressure in the eye (the intraocular pressure, IOP). Selective laser trabeculoplasty (SLT) is an ophthalmic laser intervention with the purpose of reducing the IOP. SLT can be performed in different ways, with four of the treatment protocols being evaluated in the Optimal SLT (OSLT) trial. SLT is a repeatable procedure, but scientific evidence is scarce regarding more than one repetition. In this trial, patients included in the OSLT trial will be invited to the extended trial (OSLT-R), for further follow-up and re-treatment with SLT, if needed.

NCT ID: NCT04994457 Enrolling by invitation - Glaucoma Clinical Trials

Patient Performance on Virtual Reality Visual Field Devices as Compared to Standard of Care

Start date: October 30, 2021
Phase:
Study type: Observational

The purpose of this research is to study the effectiveness and patient experience when measuring visual fields using virtual reality goggles.

NCT ID: NCT04722861 Enrolling by invitation - Glaucoma Suspect Clinical Trials

Development of the Glaucoma Visual Functioning Questionnaire-40 and Its Psychometric Properties

Start date: September 8, 2020
Phase:
Study type: Observational

The objective of this study is to develop and test the psychometric properties of a self-report questionaire, the Glaucoma Visual Functioning Questionnaire-40 (GVFQ-40), which was designed to measure the difficulty of daily activities of glaucoma patients and evaluate the effectiveness of clinical treatment or rehabilitation interventions.

NCT ID: NCT04590651 Enrolling by invitation - Cataract Clinical Trials

Cataract Surgery in Patients With Pseudoexfoliation and Pseudoexfoliation Glaucoma

PHACOPXG
Start date: September 11, 2020
Phase: N/A
Study type: Interventional

The study aims to document the effect cataract surgery has on the pseudoexfoliation and pseudoexfoliation glaucoma eye. Details such has patient history, history of possible glaucoma, intraocular pressure, status of the eye, operation parameters and postoperative effect will be documented. The study is prospective and randomised . Patients will be divided in to two groups: in one standard phacoemulsification cataract surgery will be preformed. In the second group the anterior chamber angel will be aspirated an extra minute at the end of the case with the IA probe. The aim is to determine weather this extra aspiration will have an effect on postoperative intraocular pressure and other parameters.

NCT ID: NCT04381611 Enrolling by invitation - Surgery Clinical Trials

INTEGRAL Study: A Longitudinal Study of Surgeries and Lasers in Glaucoma: Long-term Results and Success Predictors Analysed From a Large-scale Retrospective and Prospective Glaucoma Register

Start date: January 15, 2019
Phase:
Study type: Observational [Patient Registry]

The study is an observational analysis of patients' medical data recorded in a large-scale register, both retrospective (for patients operated and data recorded before 2018) and prospective (for data collected after 2018) in nature.Patients' medical data contained in the register will be analysed to determine the efficacy of the treatments they received during their follow-up at the investigation centre.

NCT ID: NCT04342052 Enrolling by invitation - Glaucoma Clinical Trials

Glaucoma After Congenital Cataract Surgery

Start date: January 1, 2011
Phase:
Study type: Observational

To determine the incidence of glaucoma following bilateral congenital cataract removal and estimate the associated risk factors in a large cohort to provide guidance for clinical practice.

NCT ID: NCT04323930 Enrolling by invitation - Primary Glaucoma Clinical Trials

eyeWatch vs. Trabeculectomy RCT (evT)

evT
Start date: June 30, 2021
Phase: N/A
Study type: Interventional

The confirm the performance and safety of the eyeWatch System as first-line filtering surgery and compare its outcomes to trabeculectomy

NCT ID: NCT04010994 Enrolling by invitation - Glaucoma Clinical Trials

Treatment of Patients With Optic Nerve Damage Patients Using Electrostimulation

HomeStim
Start date: August 5, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

The aim of the present study is to investigate the possibilities of visual field enhancement with electrical stimulation (ES) as a home stimulation method, in a total of 50 patients with optical neuropathy, who have already been treated with ES in the past. Furthermore, factors responsible for response variability and treatment effectiveness are also explored: (i) the role of mental stress (or stress resilience), (ii) the status of biomarkers, such as the systemic stress hormone levels and blood supply to the eye and brain (specifically vascular dysregulation) and (iii) the influence of personality, anxiety, depression and lifestyle. The study serves to further validate this ES procedure for the treatment of visual impairment. Specifically, better efficacy, better compliance, lowest response variability are expected after long-term home use.

NCT ID: NCT03891446 Enrolling by invitation - Ocular Hypertension Clinical Trials

Long-term Safety and Efficacy Extension Trial of Bimatoprost SR

Maia
Start date: March 27, 2019
Phase: Phase 3
Study type: Interventional

This study will evaluate the long-term safety and efficacy of Bimatoprost Sustained Release (SR) in patients with open-angle glaucoma or ocular hypertension who completed 1 of the 4 Phase 3 Bimatoprost SR studies (192024-091, -092, -093, or -095) and received Bimatoprost SR or who received commercial DURYSTA (Bimatoprost SR) in the open-label Phase 4 ARGOS study (MED-MA-EYE-0648) and completed (or exited early from) the study.